Gökçenur GÖNENÇ, Herman İŞÇİ, İlknur TÜRKMEN ÇETİNASLAN, Gülen DOĞUSOY BÜLBÜL, Mustafa ÖZGÜROĞLU, Nuray BAŞSÜLLÜ, Reyhan YAŞAR

Breast carcinoma metastasis to endometrial polyp (Case report and literature review)

Kadın genital sistemde metastazlar en sık overlerde görülür ve uterus için ekstragenital organlardışından metastaz alımı çok nadirdir. Endometrial polipe metastaz ististani bir durum olup,literatürde olgu sunumları şeklinde yer almaktadır. Sunulan olgu 52 yaşında, metastatik invazivduktal tip meme karsinomu olan kadın hastadır. Hasta jinekoloji bölümüne postmenapozal kanamaşikayeti ile başvurdu. Patolojik incelemede hiperplastik tipte endometrial polip ve fokal bir alandastroma içinde epiteloid hücre infiltrasyonu izlendi. İmmunohistokimyasal incelemede buhücrelerin CD10 negatif, Pansitokeratin ve GCDFP-15 ile pozitif olduğu görüldü. Patolojik tanıfokal karsinom infiltrasyonu (meme kanseri ile uyumlu) içeren hiperplastik polip olarakraporlandı. Meme karsinomu tanısı ile takip edilen hastalara ait küretaj materyalleri patolojirutininde sıkça yer almaktadır. Metastatik hastalık olasılığı akılda tutulmalı, materyalin tamamıincelemeye alınmalı ve patolojik inceleme; metastatik hastalığı ekarte etmek üzere dikkatleyapılmalıdır.

Endometrial polipe metastaz yapan meme karsinomu- olgu sunumu ve literatürün gözden geçirilmesi

Metastasis to female genital tract are most commonly seen in the ovaries and it is very rare foruterus to have metastasis from extragenital organs. Metastatic carcinoma in an endometrial polypis exceptional and presented as case reports in the literature. The presented case was a 52 year oldwoman, having metastatic breast carcinoma of invasive ductal type. She admitted to thegynecology department, with the complaint of postmenapausal bleeding. The pathologicalexamination revealed a hyperplastic endometrial polyp, having a focus of epiteloid cellularinfiltration in the stroma. The immunohistochemical staining showed these cells to be CD 10negative, Pancytkeratin and GCDFP-15 positive. Pathological diagnosis was hyperplastic polyp,with focal carcinoma infiltration (compatible with breast carcinoma). The curettage specimens ofthe patients being followed for breast carcinoma is frequently seen in the daily routine of thepathology. The probability of metastatic disease must be kept in mind and the whole curretagematerials must be evaluated. The pathological examination must be carefully made for theexclusion of a metastatic carcinoma.

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