Zafer KOÇ, Gürcan ERBAY, Elif KARADELİ

Radiologic findings mimicking acute abdomen in a patient with colorectal cancer: are these side effects of FOLFIRI therapy?

Bağırsak perforasyonu, akut batını işaret eden tehlikeli bir problemdir. Bilgisayarlı tomografi (BT), akut batını olan hastaları değerlendirmede kullanılan önemli bir metoddur. BT, anotomik detayları ve bağırsak duvarını göstermekte, çevre mezenterde bağırsak hastalığı ile ilgili ikincil işaretleri değerlendirmekte ve peritonel kavitede oral kontrast sızıntıları ya da az miktarda ekstraluminal havayı saptamaktadır. Bu makalenin amacı, kolorektal kanserli hastada FOLFIRI tedavisine bağlı olarak akut batının BT bulgularını açıklamaktır. İlginç olarak, bu hastanın radyolojik bulgularının aciliyeti olmasına rağmen, hasta kendini iyi hissetmekte ve klinik olarak acil bir problemi bulunmamaktadır

Kolorektal kanserli hastada akut batını taklit eden radyolojik bulgular: FOLFIRI tedavisinin yan etkileri mi?

Bowel perforation is an emergency problem, it presents as an acute abdomen. Computurize tomography (CT) is important imaging modality used to evaluate patients with acute abdomen. CT shows anatomical detail and intestinal wall, evaluating secondary signs of bowel disease within the surrounding mesentery and detecting even small amounts of extraluminal air or oral contrast leakage into the peritoneal cavity. The aim of this article is to illustrate acute abdominal CT findings due to FOLFIRI therapy of a patient with colorectal cancer. Interestingly, this patient was an emergency case based on radiologic findings, but he felt good, had no emergency problem clinically

PDF

___

1. Maniatis V, Chryssikopoulos H, Roussakis A, Kalamara C, Kavadias S, Papadopoulos A et al. Perforation of the allimentary tract: evaluation with computed tomography. Abdom Imaging. 2000;25:373-9.
2. Yeung KW, Chang MS, Hsiao CP, Huang JF. CT evaluation of gastrointestinal tract perforation. Clin Imaging. 2004;28:329-3.
3. Hainaux B, Agneessens E, Bertinotti R, De Maertelaer V, Rubesova E, Capelluto E et al. Accuracy of MDCT in predicting site of gastrointestinal tract perforation. AJR Am J Roentgenol. 2006;187:1179-83.
4. Rubesin SE, Levine MS. Radiologic diagnosis of gastrointestinal perforation. Radiol Clin North Am 2003;41:1095-115.
5. Butela ST, Federle MP, Chang PJ, Thaete FL, Peterson MS, Dorvault CJ et al. Performance of CT in detection of bowel injury. AJR Am J Roentgenol. 2001;176:129-35.
6. Boyiadzis MM, Lebowitz PF, Frame JN, Fojo T. Hematology-Oncology Therapy. New York, McGraw Hill, 2007.
7. Tournigand C, André T, Achille E, Lledo G, Flesh M, Mery-Mignard D et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol. 2004; 15: 229-37.
8. Florit-Sureda M, Conde-Estévez D, Vidal J, Montagut C. Hypersensitivity reaction caused by folinic acid administration: a case report and literature review. J Chemother. 2015; doi:10.1179/1973947815Y.0000000048.