Erken gelişen koroner arter hastalığının değerlendirilmesinde geleneksel risk faktörlerinin prediktif değeri

Amaç: Bu çalışmanın amacı genç hastalarda koroner arter hastalığının (KAH) sıklığını ve risk faktörlerini değerlendirmektir.Gereç ve Yöntem: Ocak 2000 - Mart 2016 tarihleri arasında koroner anjiyografi yapılan 21514 hastanın tıbbi kayıtları tarandı. 45 yaşından büyük ve ağır kapak hastalığı olan hastalar çalışma dışı bırakıldı. Çalışmaya toplam 862 hasta dahil edildi. KAH için başlıca risk faktörleri değerlendirilmiştir.Bulgular: Çalışılan toplam 862 hastanın 595'inde KAH, 267'sinde normal koroner arter (NKA) vardı. genç KAH grubunda erkek yüzdesi (% 94,1 vs. % 58.8) ve sigara içme oranı (% 78 vs. % 45) yaşları açısından benzer olan NKA grubuna göre yüksekti. KAH hastalarında obezite oranı kadınlarda erkeklerden daha yüksek iken (% 41 vs. % 14), sigara içme oranı erkeklerde kadınlara göre daha yüksekti (% 80 vs. % 44). Çok değişkenli analizlere göre erkek cinsiyet [Olasılık Oranı (OO) = 7,3,% 95 Güvenlik aralığı (GA) 4,6-11,4] ve sigara (OO = 2,3,% 95 GA 1,6 – 3,2) KAH'ın bağımsız belirleyicileri olarak bulundu.Sonuç: Genç erişkinlerde sigara içmenin en önemli risk faktörü olduğunu gösterdik

Anahtar Kelimeler:

Kardiyovasküler Hastalıklar, genç erişkin, risk faktörleri

Predictive value of traditional risk factors in the assessment of premature coronary artery disease

Purpose: The purpose of this study was to assess frequency, risk factors of young patients with coronary artery disease (CAD).Materials and Methods: Medical recordings of 21514 patients who underwent coronary angiography were screened for this study between January 2000 and March 2016. Patients older than 45 years old and severe valvular disease were excluded study. A total 862 patients ıncluded study. Major risk factors for CAD were identified. Results: Out of total 862 patients studied, 595 had CAD and 267 had normal coronary arteries (NCA). The young CAD group had a significantly higher proportion of males (94.1 vs. 58.8%) and smokers (78 vs. 45%) than age-matched control patients with NCA. In patients with CAD, the rate of obesity was higher in female group than males (41 vs. 14 %) while the smoking rate was higher than female group (80 vs. 44 %). According to multivariate analysis male sex [Odds ratio (OR) = 7.3, 95% Confidence interval (CI) 4.6- 11.4] and smoking (OR= 2.3, 95% CI 1.6- 3.2) were found to be independent predictors of CAD.Conclusion: We have shown that smoking was the most important risk factor in young adults

Keywords:

Cardiovascular Diseases, young adult, risk factors,

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