Meryem KÜTÜK, Gülen Güler, Ulaş GÜVENÇ, Fevziye Toros, Tamer KAYA

Çocukta alprazolama bağlı kutanöz alerjik reaksiyon

İlaca bağlı kutanöz alerjik reaksiyonlar atropin, antikonvülzanlar ve benzodiyazepinler gibi birçok ilaç türü ile ortaya çıkabilir. Fakat bezodiyazepinlere bağlı alerjik reaksiyonlar oldukça nadirdir. Alprazolam antihistaminerjik etkisinden dolayı refraktör idiyopatik ürtiker tedavisinde faydalı olabilecek bir benzodiyazepindir. Alprazolamın antihistaminerjik etkisine rağmen literatürde alprazolam ile tetiklenen bir anjioödem vakası ve bir de soğuk ürtikeri vakası bilinmektedir. Bu olguda biz tek doz alprazolamdan dolayı kutanöz alerjik reaksiyon gelişen bir çocuğu sunacağız.

Anahtar Kelimeler:

Alerji, alprazolam, çocuk, cilt reaksiyonu

Cutaneous allergic reaction due to alprazolam in a child

Cutaneous allergic reactions due to drug intake may be triggered by many types of drugs such as atropine, anticonvulsants and benzodiazepines. But allergic reactions due to benzodiazepines are extremely rare. Alprazolam is a benzodiazepine which may be useful for refractory idiopathic urticaria due to antihistaminergic effect. Although antihistaminergic effect of alprazolam, a cold urticaria case and an angioedema case induced by alprazolam are known in the literature. In the case, we present a child suffering from cutaneous allergic reaction due to alprazolam at the first dose taken.

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