Konjenital Böbrek ve İdrar Yolu Anomalisi Olan Çocukların Tek Merkezli Retrospektif Kohort Analizi

Amaç: Çalışmada konjenital böbrek ve idrar yolu anomalisi olan çocukların retrospektif epidemiyolojik, demografik ve klinik özelliklerinin paylaşılması amaçlanmıştır. Gereç ve Yöntem: Süleymaniye Kadın Doğum ve Çocuk Hastalıkları Hastanesi’nde Şubat 2016-Eylül 2017 tarihleri arasında Çocuk Nefroloji Kliniği’nde konjenital böbrek ve idrar yolu anomalisi tanısı ile takip edilen hastaların dosyaları geriye dönük olarak incelendi. Bulgular: Konjenital böbrek ve idrar yolu anomalisi nedeniyle takip edilen 117 hastadan 65’i çalışmaya dahil edildi. Bu kohortta prenatal tanı %29,2 (19), ek hastalık %27,7 (18), ailede böbrek hastalığı %32,2 (21), kompensatuvar hipertrofi %53,8 (35) ve %9,2 (6) hipertansiyon saptanmıştır. Sonuç: Akrabalık, aile böbrek hastalığı ve komorbiditesi olan hastaların kompensatuvar hipertrofisi olsa bile daha yakın takibi daha iyi olacaktır.

Anahtar Kelimeler:

konjenital, anomali, böbrek, üriner yol

Single Center Retrospective Cohort Analysis of Children with Congenital Anomaly of Kidney and Urinary Tract

Objective: The objective of the study was to determine the course of the clinical and biochemical profile of children with congenital anomalies of the kidneys and urinary tracts (CAKUT). Material and Method: The files of the patients who were followed up with the diagnosis of CAKUT in the Pediatric Nephrology Clinic between February 2016 and September 2017 in the Süleymaniye Maternity and Pediatrics Hospital were analyzed retrospectively. Results: Sixty five of 117 patients followed up for CAKUT were included in the study. In this study, we found that of the patients, 29.2% were diagnosed antenatally, 27.7% had comorbid disease, and 32.2% had family kidney disease history. Comparing with postnatal diagnosis, the patients who had pretnatal diagnosis had lower eGFR after follow up (p=0.048). There is a statistically significant relationship between consanguineous marriage and comorbidity (p=0.047, x2=3.94). Conclusion: It would be better to follow up the patients with consanguinity, family kidney disease and comorbidity closely even though they have compensatory hypertrophy.

Keywords:

Congenital anomalies, kidney, urinary tract,

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