Sinan Mahir KAYIRAN, Berkan GÜRAKAN, Aygün DİNDAR

İntravenöz İmmünglobulin Tedavisine Dirençli Kawasaki Vakası

Kawasaki hastalığı nedeni ve patogenezi bilinmeyen akut multisistemik bir vaskülittir. Tanısı klinik bulgulara göre konulur. Bu çalışmada inatçı ateş, karın ağrısı ve ishal yakınmalarıyla başvuran ve intravenöz immünglobulin IVIG tedavisine dirençli bir vaka sunulmaktadır. Hastanın yakınmaları puls metilprednizolon tedavisi ile geriledi. Yüksek doz puls steroid tedavisinin, IVIG dirençli vakalarda alternatif bir tedavi yaklaşımı olabilecektir.

Anahtar Kelimeler:

Kawasaki hastalığı, puls steroid, immünglobulin

A Case with Intravenous Immunoglobulin Resistant Kawasaki Disease

Kawasaki disease is an acute febrile multisystem vasculitis of unknown etiology and pathogenesis. The diagnosis is based on clinical features. We describe a case of intrave- nous imunoglobulins IVIG resistant Kawasaki disease presenting with persistent fever, abdominal pain and diarr- hea. The symptoms disappeared after methylprednisolone pulse therapy. We emphasize that high-dose pulse steroid may be an alternative therapeutic option in Kawasaki dise- ase which presents with failure to respond high-dose IVIG therapy

Keywords:

Kawasaki disease, pulse steroid, immunglobulin,

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