The Role of p-Coumaric Acid on Reproductive and Remote Organ Damages Created by Adnexal Torsion/Detorsion: Biochemical and Immunohistochemical A Study
The Role of p-Coumaric Acid on Reproductive and Remote Organ Damages Created by Adnexal Torsion/Detorsion: Biochemical and Immunohistochemical A Study
Objective: We planned to search the effects of p-coumaric acid on ovary and lung injuries formed via bilateral adnexal torsion detorsion (T/D) in experimental rat model.
Methods: 24 female, Sprague-Dawley rats were sorted out as 3 groups. Design of the groups was performed as sham (group I) and T/D (group II), p-coumaric acid+T/D (group III) groups. Sham group; abdomen area was applied incision and repaired with no T/D model application. T/D group; 3 h of torsion phase completed and then 3 h of detorsion stage was established. P-coumaric acid+T/D group; p-coumaric acid was administered at the dose of 100 mg/kg for 15 days by oral gavage and then, T/D model was performed. Following detorsion phase, rats were sacrificed, lung and ovarian tissues were excised for biochemical and immunohistochemical evaluations.
Results: When it is compared to group I, oxidant parameters elevated significantly in group II (p
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Clin Exp Health Sci 2022; 12: 1-8 8 DOI: 10.33808/clinexphealthsci.xxx
p-Coumaric Acid on Organ Damages Original Article
How to cite this article: Tanyeli A, Ekinci Akdemir FN, Eraslan E, Guler MC, Nacar T, Comakli S, Gulcin I. The Role of p-Coumaric Acid
on Reproductive and Remote Organ Damages Created by Adnexal Torsion/Detorsion: Biochemical and Immunohistochemical A Study.
Clin Exp Health Sci 2022; 12: 1-8. DOI: 10.33808/clinexphealthsci.xxx
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