Objective: This study was planned to determine the effects of different positionchanges on hemodynamic parameters and dyspnea severity in patients with dyspnea.Methods: This was a quasi-experimental study, using a one-group, pre-test and posttestdesign. From March-December, 2015, 58 pulmonary service patients who hadbeen hospitalized due to dyspnea and various respiratory diseases were assessedfor dyspnea severity, oxygen saturation (SpO2), systolic blood pressure (SBP),diastolic blood pressure (DBP), heart rate (HR) and respiratory rate (RR).Results: According to repeated measures variance analysis of patients in the proneand orthopnea position, there was no statistically significant difference between themeasurement of dyspnea severity, O2 saturation, SBP, DBP, and RR. However, theHR of patients increased in the prone position and dyspnea severity was shown to bereduced in the orthopnea position.Conclusion: Comparing all the positions given to the patients, it was found thattowards the 15th minutes, the orthopnea position had a positive effect on patients’mean dyspnea severity, SBP and O2 saturation but a significant difference wasobserved only on the mean dyspnea severity.