Sinan TRABULUS, Murat ÖZBALAK, Eda KAYA, Tuğçe APAYDIN, Hande Mefkure Özkaya, Özer Açbay, Nurhan Seyahi

Hemodiyalize giren bir hastada tramadol sonrası gelişen rabdomiyoliz

DOI: 10.26650/cjm.2019.43.31Tramadol Hidroklorit (HCl) düşük dozlarda genellikle güvenli olan sentetik bir analjeziktir. Yan etkiler intoksikasyon vakalarında bildirilmiştir. Biz, burada nüks paratiroid kanseri tanısı bulunan 59 yaşındaki erkek hastada medikal tedaviye dirençli ciddi hiperkalsemi ve generalize ağrı olgusunu sunuyoruz. Hasta, ağrıları için Tramadol HCl reçete edildikten sonra artan ağrılara paralel olarak ilaç dozunu arttırdı ve sonunda rabdomiyoliz gelişti. Rabdomiyoliz ilacın kesilmesinden sonra tamamen geriledi, yine de hasta pulmoner emboli nedeniyle eks oldu. Tramadol HCl kullanımına bağlı rabdomiyoliz çok nadir olarak bildirilmiştir. Tramadol HCl kullanan ve generalize kas ağrısı ile prezente olan hastalarda rabdomiyoliz düşünülmelidir.

Anahtar Kelimeler:

Hiperkalsemi, paratiroid karsinomu, rabdomiyoliz, tramadol hidroklorit

Case of Rhabdomyolysis in a Patient Undergoing Hemodialysis: A Possible Association with Tramadol HCl

DOI: 10.26650/cjm.2019.43.31Tramadol hydrochloride (HCl) is a synthetic analgesic agent, which is generally safe at a low dose. Its adverse effects are reported in cases of intoxication. Here we present a 59-year-old male patient with multiple relapsing parathyroid carcinoma-related refractory hypercalcemia and generalized pain. Being prescribed tramadol HCl, he consumed an increased dosage following increased pain, resulting in rhabdomyolysis, which improved after cessation of the drug. Nevertheless, the patient died owing to pulmonary embolism. Rhabdomyolysis owing to tramadol HCl consumption is very rarely reported. Rhabdomyolysis should be considered in patients consuming tramadol HCl and having generalized muscle weakness.Cite this article as: Trabulus S, Özbalak M, Kaya E, Apaydın T, Özkaya HM, Açbay Ö, et al. Case of rhabdomyolysis in a patient undergoing hemodialysis: a possible association with tramadol HCl. Cerrahpasa Med J 2019; 43(1): 34-36.

Keywords:

Hypercalcemia, Parathyroid carcinoma, Rhabdomyolysis, Tramadol hydrochloride,

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