Fatih KARA, Eray ATALAY, Halil İbrahim ERDOĞDU, Ömer KARAAĞAÇ, Can ÖNER

SERUM FERRİTİN DÜZEYİNİN METABOLİK PARAMETRELER İLE İLİŞKİSİNİN CİNSİYETE GÖRE DEĞERLENDİRİLMESİ: BİR AKUT FAZ REAKTANI OLARAK SERUM FERRİTİNİ

Amaç: Artmış serum ferriti düzeyi depo demirini ya da hepati dokuda demir birikimini yansıtabilir. Ancakyüksek ferriti düzeyi olası kronik hepatobiliyer ya da sistemik inflmatuar hastalıklarla da ilişkili olabilmektedir. Bu çalışmada serum ferritii ile hastaya ait kan sayımı ve biyokimyasal parametreler karşılaştıılarakaralarındaki ilişkinin belirlenmesi amaçlandı.Materyal ve Metot: Kesitsel tite yapılan çalışma 110 hastanın biyokimyasal, hormonal ve tam kan sayımlarınaait verilerinin analizi ile yapıldı. Hastalar cinsiyete göre ferriti düzeyi normal ve normalin üzerinde olarak ikiguruba ayrıldı. Bağımlı değişken olarak belirlenen serum ferriti düzeyi ile hastaların yaşı, serum albümini,C-reakti proteini (CRP), serum demiri, transferrin satürasyonu (TSAT), hemoglobin düzeyi, alanin ve aspartataminotransferaz (ALT, AST) ve gama glutamil transferaz (GGT) gibi parametreler ile karşılaştııldı.Bulgular: Yapılan karşılaştımada kadınlarda normal serum ferritii ile normalin üst sınırını geçen düzeylerinALT (p=0.018), albümin (p=0.041), CRP (p=0.025), TSAT (p=0.012), LDL (p=0.024) ve trigliserid (p=0.038) dü-zeyleri arasında istatisel olarak anlamlı fark saptandı. Erkekler analiz edildiğinde ise ALT (p=0.045), albümin(p

Evaluatig Serum Ferriti Level’s Relatin with Metabolic Parameters By Gender: Serum Ferriti as an Acute Phase Reactant

Aim: Increased serum ferriti level may reflct the iron store or accumulated iron in hepati tisue. However, high level of ferriti may be about potentil chronic hepatobiliary or systemic inflmmatory diseases. In this study, by comparing serum ferriti with blood count which belongs to patint and biochemical parameters, the relatin between them is tried to be identiid. Material and Method: The data belonging to biochemical, hormonal and complete blood count were analyzed for 110 patints in this cross-sectinal study. Patints were divided into two groups, who were normal and above normal ferriti level by their genders. Serum ferriti level, which was determined as dependent variable, was compared with parameters such as patints’ ages, serum albumin, C-reactie protein (CRP), serum iron, transferrin saturatin (TSAT), hemoglobin level, alanine and aspartate aminotransferase (ALT, AST) and gama glutamic transferase (GGT). Results: In the comparison, a statitially signifiant diffrence between ALT (p=0.018), albumin (p=0.041), CRP (p=0.025), TSAT (p=0.012), LDL (p=0.024) and triglyceride (p=0.038) levels identiid for women who have normal serum ferriti level and level of ferriti above upper limit. There were statitially signifiant diffrence between ALT (p=0.045), albumin (p

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