HEMOPTİZİ: TANISAL YÖNTEMLERİN KARŞILAŞTIRILMASI VE AKCİĞER KANSERİ İÇİN RİSK FAKTÖRLERİNİN BELİRLENMESİ
Amaç: Hemoptizinin farklı etyolojik nedenlerinin sıklığını, bilgisayarlı akciğer tomografisi, bronkoskopinin tanısal başarısını ve cut-off değerleriyle akciğer kanseri için risk faktörlerini belirlemeye çalıştık.Gereç ve Yöntemler: Bozok Üniversitesi ve Yozgat Devlet Hastanesinde mayıs 2009 ve ocak 2012 tarihleri arasında hemoptizisi olan 80 hasta retrospektif incelendi.Bulgular: Hastalar yaş ortalaması 48.1±10.71 yıl olan 47 (58.8%) erkek ve 33(41.2%) kadından oluşmaktadır. Hemoptizinin ana etyolojisi bronşiektazi (42.5%) takiben akciğer kanseri (17.5%), pnömoni (15%), akciğer absesi (8.8%) ve idiopatik (16.2%) idi. Akciğer tomografisinin tanısal başarısı 52.5% ve bronkoskopinin 37.5% iken beraber kullanıldıklarında başarı 83.8% olmaktadır. Kanser ve kanser-dışı grup arasında yaş (p
Hemoptysis: Comparison of Diagnostic Modalities, and Prediction of Risk Factors of Lung Cancer
Background: We aimed to identify the relative frequency of different etiologies of hemoptysis, diagnostic yield of computerized chest tomography, bronchoscopy and risk factors for lung cancer with their cut-off levels.Method: We reviewed 80 patients with hemoptysis retrospectively at the Yozgat State Hospital and Bozok University Hospital, Yozgat, Turkey between May 2009 and January 2012. Results: There were 47 male (58.8%) and 33 female (41.2%) patients with a mean age of 48.1±10.71 years. The main etiology of hemoptysis was bronchiectasis (42.5%), followed by lung cancer (17.5%), pneumonia (15%), lung abscess (8.8%) and idiopathic (16.2%). The diagnostic yield of chest CT was 52.5% and that of bronchoscopy was 37.5% while the yield was 83.8% together. There was statistically significant difference between cancer and non-cancer group patients in terms of age (p
___
- 1. Dorland’s Illustrated Medical Dictionary. 28th ed. Philadelphia: W.B. Saunders Company, 1994. pg. 750.
- 2. Ozlu T. Massif Hemoptizi. In: Ekim N, Türktaş H (edit). Göğüs Hastalıkları Acilleri. 1st ed., Ankara, Bilimsel Tıp Yayınevi, 2000. p. 241-6.
- 3. Fishman AP. Approach to the patient with respiratory symptoms. In: Fishman AP (edit). Fishman’s pulmonary diseases and disorders. 4th ed., New York, McGraw-Hill, 2008. p. 387-425.
- 4. Hirshberg B, Biran I, Glazer M, Kramer MR. Haemoptysis Aetiology, evaluation and outcome in a tertiary referal hospital. Chest. 1997;112(2):440-4.
- 5. Fidan A, Ozdogan S, Oruç O, et al. Hemoptysis: A retrospective analysis 108 cases. Respir Med. 2002;96(9):677-80.
- 6. Santiago S, Tobias J, Wiiliams AJ. A reappraisal of the causes of haemoptysis. Arch Intern Med. 1991;151(12):2449-2451.
- 7. McGuinness G, Beacher JR, Harkin TJ. Hemoptysis: Prospective high-resolution CT/ bronchoscopic correlation. Chest. 1994;105(4):1155-62.
- 8. Tsoumakidou M, Chrysofakis G, Tsiligianni I, et al. A prospective analysis of 184 hemoptysis cases: diagnostic impact of chest X-ray, computed tomography, bronchoscopy. Respiration. 2006;73(6):808-14.
- 9. Prasad R, Garg R, Singhal S, Srivastava P. Lessons from patients with hemoptysis attending a chest clinic in India. Ann Thorac Med. 2009;4(1):10-2.
- 10. Abal AT, Nair PC and Cherian J. Haemoptysis: Aetiology, evaluation and outcome a prospective study in a third world country. Respir Med. 2001;95(7):548-52.
- 11. Unsal E, Köksal D, Çimen F, Hoca NT, Şipit T. Analysis of patients with hemoptysis in a reference hospital for chest diseases. Tuber Thorax. 2006;54(1):34-42.
- 12. Özgül MA, Turna A, Yıldız P, Ertan E, Kahraman S, Yılmaz V. Risk factors and recurrence patterns in 203 patients with hemoptysis. Tuber Thorax. 2006;54(3):243-8.
- 13. Lee BR, Yu JY, Ban HJ, OhIJ, Kim KS, Kwan YS. Analysis of patients with hemoptysis in a tertiary referral hospital. Tuberc Respi Dis. 2012;73(2):107-114.
- 14. Abbott OA. The clinical significance of pulmonary hemorrhage: A study of 1316 patients with chest disease. Dis Chest. 1948;14(6):824-42.
- 15. Johnston H, Reisz G. Changing spectrum of hemoptysis. Underlying causes in 148 patients undergoing diagnostic flexible fiberoptic bronchoscopy. Arch Intern Med. 1989;149(7):1666-8.
- 16. Nawal SK, Heda MR. Hemoptysis: A prospective analysis of 110 cases. Asian Journal of Biomedical and Pharmaceutical Sciences. 2013;3(21):1-3.
- 17. Wong CM, Lim KH, Liam CK. The causes of hemoptysis in malaysian patients aged over 60 and the diagnostic yield of different investigations. Respirology. 2003;8(1):65-8.
- 18. Stebbings AE, Lim TK. Cause, treatment and outcome of patients with life-threatening haemoptysis. Singapore Med J. 1999;40(2):67-9
- 19. Soares Pires F, Teixeira N, Coelho F, Damas C. Hemoptysis--etiology, evaluation and treatment in a university hospital. Rev Port Pneumol. 2011;17(1):7-14.
- 20. Celik P, Gönlügür U, Akın M, Orman A. Hemoptizili Olgularımızın Analizi. Heybeliada Tıp Bült1997;3:45-8.
- 21. Dogan OT, Berk S, Engin A, Akkurt I. Hemoptizide etyolojik faktörler. Cumhuriyet Tıp Derg. 2010; 32(1):48-53.
- 22. Weaver LJ, Solliday N, Cugell DW. Selection of patients with hemoptysis for fiberoptic bronchoscopy. Chest. 1979;76(1):7-10.
- 23. Davoodi M, Kordi M, Gharibvand MM, Shoushtari MH, Borsi H, Bahadoram M. Hemoptysis: Comparision of diagnostic accuracy of multi detector ct scan and bronchoscopy. Glob J Health Sci. 2015;7(3):373-7.
- 24. Senyigit A, Bayram H, Asan E et al. The value of fiberoptıc bronchoscopy and high-resolution ct in investigating hemoptysis of patients with normal chest x-ray. Solunum Hast. 2001;12(2):123-8.
- 25. Poe RH, Israel RH, Marin MG, et al. Utility of fiberoptic bronchoscopy in pateints with haemoptysis and a nonlocalizing chest roentgenogram. Chest. 1988;93(1):70-5.
- 26. Herth F, Ernst A, Becker HD. Long-term outcome and lung cancer incidence in patients with hemoptysis of unknown origin. Chest. 2001;120(5):1592-4.