Ayşe Seza İNAL, Süheyla KÖMÜR, Selçuk NAZİK, AKSU Hasan Salih Zeki, Aslıhan ULU, Behice KURTARAN, Yeşim TAŞOVA

BİR OLGU İLE ERİŞKİN STİLL HASTALIĞI

Erişkin Still hastalığı (ESH); akut, inflamatuar, febril bir hastalıktır. Yüksek ateş, artralji, miyalji, art- rit, boğaz ağrısı, makülopapüler raş, lenfadenopati, hepatosplenomegali ve lökositoz belirgin kli- nik bulgulardır. Laboratuvar tetkiklerinde çok yüksek ferritin değerleri, en patognomik bulgudur.Tanı genellikle diğer hastalıklar dışlandıktan sonra Yamaguchi kriterleri kullanılarak konulur. Buçalışmada nedeni bilinmeyen ateş (NBA) etiyolojisi araştırılmak üzere yatırılan ve ESH tanısı konanbir olgunun sunulması amaçlanmıştır.

A Case of Adult Still s Disease

Adult-onset Still s disease (AOSD) is an acute, inflammatory, febrile disorder. Its significantclinical findings are high fever, arthralgia, myalgia, arthritis, sore throat, maculopapular rash,lymphadenopathy, hepatosplenomegaly, and leukocytosis. The most pathognomonic laboratorytest finding is very high ferritine levels. Diagnosis is usually made using Yamaguchi criteria afterexcluding other diseases. In this study, we aimed to present an AOSD case that was hospitalized toinvestigate the etiology of fever of unknown origin (FUO).

PDF

___

1. Kahn MF. Adult Stills disease. Still many issues unresolved. J Rheumatol 1996;23(21):2015-16.
2. Ohta A, Yamaguchi M, Tsunematsu T, Kasukawa R, Mizushima H, Kashiwagi H et al. Adult Stills disease: a multicenter survey of Japanese patients. J Rheumatol 1990;17(12):1058-63.
3. John M Esdaile. Juvenil chronic arthritis. Adult Stills Disease. In: Klippel JH, Dieppe PA.Rheumatology. London: London Mosby Limited, 1998. p 1-8.
4. Fautrel B. Adult-onset still disease. Best Pract Res Clin Rheumatol 2008; 22(8): 773-92.
5. Yamaguchi M, Ohta A, Tsunematsu T, Kasukawa R, Mizushima Y, Kashiwagi H et al. Preliminary criteria for classification of adult Stills disease. J Rheumatol 1992; 19(5): 424-30.
6. Masson C, Le Loet X, Liote F, Dubost JJ, Boissier MC, Perroux-Goumy L et al. Comparative study of 6 types of criteria in adult Stills disease. J Rheumatol 2006;23(5):495-7.
7. Pay S, Türkçapar N, Kalyoncu M, Simşek I, Beyan E, Ertenli I et al. A multicenter study of patients with adult-onset Stills disease compared with systemic juvenile idiopathic arthritis. Clinical Rheumatology 2006;25(7):639-44.
8. Cagatay Y, Gul A, Cagatay A, Kamali S, Karadeniz A, Inanc M et al. Adult-onset Stills disease. Int J Clin Pract 2009;63(12):1050-5.
9. Mert A, Ozaras R, Tabak F, Bilir M, Ozturk R, Ozdogan H et al. Fever unknown origin: a review of 20 patients with adult onset Stills disease. Clin Rheumatol 2003;22(1):89-93.
10. Mok CC, Lau CS, Wong RW. Clinical characteristics,treatment and outcome of adult onset Stills disease in southern Chinese. J Rheumatol 1998;25(22):2345-51.
11. Esdaile JM. Tannenbaum H, Hawkins D. Adult Stills disease. Am J Med 1980; 68(8): 825-30.
12. Reginato AJ, Schumacher HR, Baker Jr DG, OConnor CR, Ferreiros J. Adult onset Stills disease: Experience in
23 patients and literature review with emphasison organ failure. Semin Arthritis Rheum 1987; 17(1): 39-57.
13. Uppal SS, Al-Mutairi M, Hayat S, Abraham M, Malaviya A. Ten years of clinical experience with adult onset Stills disease: is the outcome improving? Clin Rheumatol 2007;26(12):1055-60.
14. Evensen KJ, Nossent HC. Epidemiology and outcome of adult-onset Stills disease in Northern Norway. Scand J Rheumatol 2006;35(1):48-51.
15. Pouchot J, Sampalis JS, Beaudet F, Carette S, Décary F, Salusinsky-Sternbach M et al. Adult Stills disease: Manifestations, disease course and outcome in 62 patients. Medicine (Baltimore) 1991; 70(12): 118-36.
16. Van de Putte LB, Wouters JM. Adult onset Stills disease. Baillieres Clinical Rheumatology 1991; 5(2): 263-75.
17. Akritidis N, Giannakakis Y, Sakkas L. Very high serum ferritin levels in adult-onset Stills disease. Br J Rheumatol 1996;36(7):608.
18. Sampalis JS, Esdaile JM, Medsger TA Jr, Partridge AJ, Yeadon C, Senécal JL et al. A controlled study of long-term prognosis of adult Stills disease. Am J Med 1995;98(4):384-8.