The global outbreak of COVID-19 has profoundly changed our lives and professional practice. During the rapid switch to fully-online education, both teachers and students faced several challenges as it was a novel situation. This special issue of the Boğaziçi University Journal of Education aims to address this issue by focusing on distance teaching and learning practices during the COVID-19 Pandemic, focusing on challenges encountered and responses of teachers and students. Including research studies conducted in different contexts, the special issue also highlights the worldwide impact of the pandemic in educational processes and how challenges resulting from the pandemic have been resolved in different countries.