Nuraniye ERUYGUR, Özge ÇEVİK, Mehmet ATAŞ, Mehmet TEKİN

Chemical Characterization and Biological Activity Evaluation of Essential Oils of Achillea Sipikorensis, an Endemic Plant from Turkey

The Achillea L. (Asteraceae) are known all over the world and used widely by local people as folk herbal medicine. The species are reported to have anti-inflammatory, antioxidant, diuretic, antispasmodic vs. activities and have been used for the treatment of various ailments in Turkish traditional medicine. This work it the first study on chemical composition and biological activity of essential oil obtained from endemic plant- A. sipikorensis Hausskn. Et. Bornm evaluated for their antiradical, antimicrobial and cytotoxic activities. GC/MS analyses showed that cis- chrysanthenol (14.5%), 1, 8-cineol (10.9%), caryophyllene oxide (8.5%), borneol (8.2%), and camphor (6.1%) were the major constituents in the essential oil from aerial part of the plant. The essential oil demonstrated good antioxidant, antimicrobial and cytotoxic activities.

Keywords:

Achillea sipikorensis, Essential oil, Antioxidant, Antimicrobial,

PDF

___

Abu Zarin, M., Wan, H.Y., Isha, A., Armania, N., 2016. Antioxidant, antimicrobial and cytotoxic potential of condensed tannins from Leucaena leucocephala hybrid-Rendang. Food Sci. Hum. Wellness 5, 65–75. doi:10.1016/j.fshw.2016.02.001
Awouafack, M.D., McGaw, L.J., Gottfried, S., Mbouangouere, R., Tane, P., Spiteller, M., Eloff, J.N., 2013. Antimicrobial activity and cytotoxicity of the ethanol extract, fractions and eight compounds isolated from Eriosema robustum (Fabaceae). BMC Complement. Altern. Med. 13, 289. doi:10.1186/1472-6882-13-289
Blois, M.., 1958. Antioxidant determination by the use of a stable free radical. Nature 181, 1199–1200.
D, H., 1992. Free radical theory of aging: history. EXS 62, 1–10.
Honda, G., Yeşilada, E., Tabata, M., Sezik, E., Fujita, T., Takeda, Y., Takaishi, Y., Tanaka, T., 1996. Traditional medicine in Turkey. VI. Folk medicine in west Anatolia: Afyon, Kütahya, Denizli, Muğla, Aydin provinces. J. Ethnopharmacol. 53, 75–87. doi:10.1016/S0378-8741(96)01426-2
Karaalp, C., Yurtman, A.N., Yavasoglu, N.U.K., 2009. Evaluation of antimicrobial properties of Achillea L. flower head extracts. Pharm. Biol. 47, 86–91. doi:10.1080/13880200802448682
Manayi, A., Mirnezami, T., Saeidnia, S., Ajani, Y., 2012. Pharmacognostical Evaluation, Phytochemical Analysis and Antioxidant Activity of the Roots of Achillea tenuifolia LAM. Pharmacogn. J. 4, 14–19. doi:10.5530/pj.2012.30.3
Ozlem Toncer, Sema Basbag, Sengul Karaman, Emel Dıraz, M.B., 2010. Chemical Composition of the Essential Oils of some Achillea Species Growing Wild in Turkey. Int. J. Agric. Biol. 12, 527–530.
Roberta Re, Nicoletta Pellegrini, Anna Proteggente, Ananth Pannala, Min Yang, C.R.-E., 1999. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic. Biol. Med. 26, 1231–1237.
Saeed, N., Khan, M.R., Shabbir, M., 2012. Antioxidant activity, total phenolic and total flavonoid contents of whole plant extracts Torilis leptophylla L. BMC Complement. Altern. Med. 12, 1174. doi:10.1186/1472-6882-12-221
Saeidnia, S., Gohari, A., Mokhber-Dezfuli, N., Kiuchi, F., 2011. A review on phytochemistry and medicinal properties of the genus Achillea. Daru 19, 173–86.