İrritabl Bağırsak Sendromlu Hastalarda Laktoz İntoleransı ve Osteoporoz Gelişimi

İrritabl bağırsak sendromu (IBS), gastrointestinal sistem hastalıkları arasında en sık görülen kronik fonksiyonel bozukluklardan biridir. Dünya genelinde prevalansı yüksek olan IBS, hastaların yaşam kalitesini olumsuz yönde etkilemektedir. IBS'nin gelişiminde etkili olan mekanizmalar tam olarak anlaşılamamıştır. Ancak mekanizmasının multifaktöriyel olduğu düşünülmektedir. IBS, karın ağrısı, ishal, kabızlık, gaz ve hazımsızlık gibi belirli semptomlarla karakterizedir. Bununla birlikte, bu semptomlar IBS'ye özgü değildir ve sıklıkla laktoz intoleransı (LI) semptomları ile karşılaşılabilmektedir. Öte yandan İBS hastalarında aynı anda LI görülme olasılığı oldukça yüksektir. IBS hastaları, semptomlarını tetikledikleri düşüncesiyle laktoz içeren gıdaları özellikle süt ve süt ürünlerini kısıtlamakta ve bunun sonucunda kalsiyum eksikliği oluşabilmektedir. Bu hastaların uzun süre yetersiz kalsiyum alması sonucunda osteoporoz ve osteoporotik kırık riski önemli bir sorun haline gelmektedir. Tüm bu faktörler doğrultusunda bu derleme, İBS hastalarında LI varlığına bağlı olarak gelişebilecek osteoporozu incelemeyi ve beslenme önerilerinde bulunmayı amaçlamaktadır.

Lactose Intolerance and Osteoporosis Development in Irritable Bowel Syndrome Patients

Irritable bowel syndrome (IBS) is one of the most common chronic functional disorders among gastrointestinal system diseases. IBS, which has a high prevalence worldwide, negatively affects the quality of life of patients. The mechanisms that are effective in the development of IBS has not clearly been defined. However, its mechanism is thought to be multifactorial. IBS is characterized by certain symptoms, such as abdominal pain, diarrhea, constipation, flatulence, and indigestion. Nevertheless, these symptoms aren’t specific to IBS and can often be confused with lactose intolerance (LI) symptoms. On the other hand, the probability of having LI at the same time is quite high in IBS patients. IBS patients restrict lactose-containing foods, especially milk and dairy products, due to the thought that they trigger their symptoms, and thus calcium deficiency may occur as a result. Due to insufficient calcium intake for a long time, the risk of osteoporosis and osteoporotic fractures becomes an important problem. In line with all these factors, this review aims to examine osteoporosis that may develop due to the presence of LI in IBS patients and to make nutritional recommendations.

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Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi-Cover
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 2019
  • Yayıncı: Bandırma Onyedi Eylül Üniversitesi
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