Kanser Hastalarında İki Yıllık Subkutan Venöz Port Kateter Deneyimimiz

Amaç:Bu çalışmada malignite tanısı ile port kateter implante edilen hastaların retrospektif olarak incelenmesi ve takipleri sırasında meydana gelmiş olan komplikasyonların ortaya konulması amaçlanmıştır. Gereç-Yöntem: 2017 Eylül-2019 Eylül tarihleri arasında XXX Hastanesi Cerrahi Onkoloji KliniğindeSubkutan Venöz Port Kateter (SVPK) takılan toplam 109 hasta (67 erkek, 42 kadın) (yaş ortalaması±standart sapma=59.68 ±11.84) retrospektif olarak incelenmiş demografik veri, venöz erişim yolu, teknik ve komplikasyonlar ortaya konulmuştur. Bulgular: En sık SVPK takılan malignitenin kolon kanseri olduğu görülmüştür. Erken dönem komplikasyonlardan Sağ İnternal Jugüler Ven (İJV)’den yapılan girişimlerde sekiz (%8.42) hastada giriş yerinde hematom, dört (%4.21) hastada tünel bölgesi hematomu, altı (%6.31) hastada tünel bölgesi ekimozu görülürken, Sağ Subklavien Ven (SCV)’den yapılan girişimlerde bir (%7.14) hastada giriş yerinde hematom ve bir (%7.14) hastada kateter malpozisyonu görülmüştür. Hastalarda pnömotorak/hemotoraks gelişmemiştir. Geç dönem komplikasyonlarında da İJV’den girişimlerinde altı (%6.31) hastada cilt enfeksiyonu, iki (%2.10) hastada rezervuar malrotasyonu, iki (%2.10) hastada fibrin tıkaç, iki (%2.10) hastada da kateter katlanması görülmüştür. SCV’den yapılan girişimlerde ise iki (%14.28) hastada cilt enfeksiyonu, bir (%7.14) hastada fibrin tıkaç görülmüştür. “Pinch off sendromu” ve venöz tromboz görülmemiştir. İki giriş yolunda komplikasyonlar açısından istatistiksel olarak anlamlı fark saptanmamıştır. İJV’den yapılan girişimlerde altı (%6.31), SCV’den girişim yapılan iki (%14.28) hastada çeşitli nedenlerle kateterler çıkarılırken, İJV’den girişim yapılan üç (%3.15) hastada kateter revizyonu yapılmıştır. Sonuç:Subkutan venöz port kateteri kanser hastalarında etkin ve güvenilir bir venöz erişim yoludur. Uygun teknik ve tecrübeli ellerde yapıldığı taktirde minimal komplikasyon ve uzun süreli bir venöz erişim yolu sağlamaktadır.

Our Two-Year Experience with the Subcutaneous Venous Port Catheter in Cancer Patients

Objective: In this study, it was aimed to retrospectively examine the patients who were implanted with a port catheter with the diagnosis of malignancy and to reveal the complications that occurred during their follow-up. Materials and Methods: Demographic data, venous access route, technique and complications of a total of 109 patients who were inserted Subcutaneous Venous Port Catheter (SVPK) between September 2017 and September 2019 in Aydın State Hospital Surgical Oncology Clinic were retrospectively analyzed. Results: The most common malignancy with CVPK was colon cancer. In the interventions made from the Right Internal Jugular Vein (IJV), one of the early complications, eight (8.42%) patients had a hematoma at the access site, four (4.21%) had tunnel site hematoma, six (6.31%) had tunnel zone ecchymosis, and Right Subclavian Vein (SCV) in one (7.14%) patient, hematoma at the entry site and catheter malposition in one (7.14%) patient. In late complications, skin infection in six (6.31%) patients, reservoir malrotation in two (2.10%) patients, fibrin plug in two (2.10%) patients, and catheter folding in two (2.10%) patients were observed in IJV interventions. In interventions made from SCV, skin infection was observed in two (14.28%) patients and fibrin plug was observed in one (7.14%) patient. “Pinch off syndrome” and venous thrombosis were not observed. No statistically significant difference was found in terms of complications in the two access routes. Conclusion: Subcutaneous venous port catheter is an effective and safe venous access method in cancer patients. Provides minimal complications and a long-term venous access route if performed with appropriate technique and experienced hands.

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  • Biffi, R., De Braud, F., Orsi, F., Pozzi, S., Arnaldi, P., Goldhirsch, A., ... & Andreoni, B. (2001). A randomized, prospective trial of central venous ports connected to standard open‐ended or Groshong catheters in adult oncology patients. Cancer: Interdisciplinary International Journal of the American Cancer Society, 92(5), 1204-1212. https://doi.org/10.1002/1097- 0142(20010901)92:5<1204:AIDCNCR1439>3.0.CO;2-9
  • Burns, K. E., & McLaren, A. (2009). Catheter-related right atrial thrombus and pulmonary embolism: a case report and systematic review of the literature. Canadian Respiratory Journal, 16(5), 163-165. https://doi.org/10.1155/2009/751507
  • Cowl, C., Weinstock, J. V., Al-Jurf, A., Ephgrave, K., Murray, J. A., & Dillon, K. (2000). Complications and cost associated with parenteral nutrition delivered to hospitalized patients through either subclavian or peripherally-inserted central catheters. Clinical Nutrition, 19(4), 237-243. https://doi.org/10.1054/clnu.2000.0103
  • Czepizak, C. A., O’Callaghan, J. M., & Venus, B. (1995). Evaluation of formulas for optimal positioning of central venous catheters. Chest, 107(6), 1662-1664. https://doi.org/10.1378/chest.107.6.1662
  • Dede, D., Akmangit, I., Yildirim, Z. N., Sanverdi, E., & Sayin, B. (2008). Ultrasonography and fluoroscopy-guided insertion of chest ports. European Journal of Surgical Oncology, 34(12), 1340-1343. https://doi.org/10.1016/j.ejso.2007.12.001
  • Di Carlo, I., Cordio, S., La Greca, G., Privitera, G., Russello, D., Puleo, S., & Latteri, F. (2001). Totally implantable venous access devices implanted surgically: a retrospective study on early and late complications. Archives of Surgery, 136(9), 1050-1053.
  • Gulec, G., & Buyukkinaci, A. (2011). Cancer and psychiatric disorders/Kanser ve psikiyatrik bozukluklar. Psikiyatride Guncel Yaklasimlar, 3(2), 343-368.
  • Güven, C. Subkutan venöz port katater uygulamalarımızın değerlendirilmesi: 6 yıllık klinik tecrübemiz. Adıyaman Üniversitesi Sağlık Bilimleri Dergisi, 6(1), 29-40. https://doi.org/10.30569/adiyamansaglik.624148
  • Iannacci, L., & Piomelli, S. (1984). Supportive care for children with cancer. Guidelines of the Childrens Cancer Study Group. Use of venous access lines. The American Journal of Pediatric Hematology/Oncology, 6(3), 277- 281.
  • Kaygın, M. A., Dağ, Ö., Güneş, M., Şenocak, M., & Erkut, B. (2012). Malign hastalıklarda intravenöz port kullanımı: 5 yıllık klinik deneyim. Selçuk Tıp Dergisi, 28(1), 17- 21.
  • Kesici, S., Carus, H., Turgut, N., Ünlü, N., Altan, A., & Kesici, U. (2011). Başarılı venöz port kateterizasyonu sonrası kateterin spontan yer değişmesi. Okmeydanı Tıp Dergisi, 27(1), 49-53.
  • Lin, C. H., Wu, H. S., Chan, D. C., Hsieh, C. B., Huang, M. H., & Yu, J. C. (2010). The mechanisms of failure of totally implantable central venous access system: analysis of 73 cases with fracture of catheter. European Journal of Surgical Oncology, 36(1), 100-103. https://doi.org/10.1016/j.ejso.2009.07.011
  • Lorch, H., Zwaan, M., Kagel, C., & Weiss, H. D. (2001). Central venous access ports placed by interventional radiologists: experience with 125 consecutive patients. Cardiovascular and İnterventional Radiology, 24(3), 180-184. https://doi.org/10.1007/s002700001721
  • McGee, D. C., & Gould, M. K. (2003). Preventing complications of central venous catheterization. New England Journal of Medicine, 348(12), 1123-1133. https://doi.org/10.1056/NEJMra0118
  • Özer, A. B., & Bayar, M. K. (2011). İmplante edilebilir venöz port kateter uygulamalarımızın incelenmesi. Fırat Tıp Dergisi, 16(1), 6-10.
  • Schwarz, R. E., Groeger, J. S., & Coit, D. G. (1997). Subcutaneously implanted central venous access devices in cancer patients: a prospective analysis. Cancer, 79(8), 1635-1640. https://doi.org/10.1002/(SICI)1097- 0142(19970415)79:8<1635::AID-CNCR30>3.0.CO;2- X
  • Shim, J., Seo, T. S., Song, M. G., Cha, I. H., Kim, J. S., Choi, C. W., ... & Oh, S. C. (2014). Incidence and risk factors of infectious complications related to implantable venous-access ports. Korean Journal of Radiology, 15(4), 494-500. https://doi.org/10.3348/kjr.2014.15.4.494
  • Singh, K. R., Agarwal, G., Nanda, G., Chand, G., Mishra, A., Agarwal, A., ... & Goyal, P. (2014). Morbidity of chemotherapy administration and satisfaction in breast cancer patients: a comparative study of totally implantable venous access device (TIVAD) versus peripheral venous access usage. World Journal of Surgery, 38(5), 1084-1092. https://doi.org/10.1007/s00268-013-2378-x
  • Stanislav, G. V., Fitzgibbons, R. J., Bailey, R. T., Mailliard, J. A., Johnson, P. S., & Feole, J. B. (1987). Reliability of implantable central venous access devices in patients with cancer. Archives of Surgery, 122(11), 1280-1283. https://doi.org/10.1001/archsurg.1987.0140023006601 2
  • Tabatabaie, O., Kasumova, G. G., Kent, T. S., Eskander, M. F., Fadayomi, A. B., Ng, S. C., ... & Tseng, J. F. (2017). Upper extremity deep venous thrombosis after port insertion: what are the risk factors? Surgery, 162(2), 437-444. https://doi.org/10.1016/j.surg.2017.02.020
  • Tan, P. L., & Gibson, M. (2006). Central venous catheters: the role of radiology. Clinical Radiology, 61(1), 13-22. https://doi.org/10.1016/j.crad.2005.07.010
  • Turcotte, S., Dube, S., & Beauchamp, G. (2006). Peripherally inserted central venous catheters are not superior to central venous catheters in the acute care of surgical patients on the ward. World Journal of Surgery, 30(8), 1605-1619. https://doi.org/10.1007/s00268-005-0174-y
  • Yildizeli, B., Lacin, T., Batirel, H. F., & Yüksel, M. (2004). Complications and management of long-term central venous access catheters and ports. The Journal of Vascular Access, 5(4), 174-178. https://doi.org/10.1177/112972980400500407
  • Yip, D., & Funaki, B. (2002). Subcutaneous chest ports via the internal jugular vein: a retrospective study of 117 oncology patients. Acta Radiologica, 43(4), 371-375. https://doi.org/10.1080/j.1600-0455.2002.430405.x
  • Yousaf, M., & Malak, S. F. (2008). Left atrial drainage of a persistent left superior vena cava. Radiology case reports, 3(4), 225. https://doi.org/10.2484/rcr.v3i4.225