Eyyup KARAHAN, Melek KÖROĞLU CANLI, Gözde ŞAHİN VURAL, Sami YILMAZ, Ercan GÖMLEKSİZ, Cenap GÜLER

Anjiografik Erken Hiperfloresansın Kistoid Diyabetik Maküler Ödem Tedavisindeki Prognostik Rolü: Anjiyografik Çalışma

Amaç: Çalışmanın amacı, fundus floresein anjiografi (FFA) görüntülerindeki floresans seviyesinin diyabetik maküler ödem prognozundaki öngördürücü değerini saptamaktır. Gereç ve Yöntem: Retrospektif tasarımlı bu çalışmada, diyabetik maküler ödem için intravitreal enjeksiyon (ranibizumab, aflibersept) tedavisi alan 21 hastanın 21 gözü değerlendirilmiştir. Demografik özelliklere ek olarak, tedavi öncesi ve sonrası en iyi düzeltilmiş görme keskinliği (EİDGK), santral retinal kalınlık (SRK) ve FFA’da erken evre floresans düzeyi kaydedilmiştir. Erken evre anjiografik florasansın tedaviye yanıt prognozunu gösterme etkisi değerlendirilmiştir. Gruplar reflektans düzeyine gore düşük ya da yüksek floresans olarak gruplandırılmıştır. Bulgular: Tedavi sonrası EİDGK anlamlı olarak artarken, ortalama SRK anlamlı olarak azalmıştır (p

The Prognostic Role of Early Hyperfluorescence in the Treatment of Cystoid Diabetic Macular Edema

Aim: To evaluate the predictive value of fluorescence level in fundus fluorescein angiography (FFA) images for the prognosis of diabetic macular edema (DME). Material and Methods: In this retrospective study, 21 eyes of 21 patients who have been treated with intravitreal injection (ranibizumab, aflibercept) for DME were evaluated. In addition to demographic features, pre/post-treatment best-corrected visual acuity (BCVA) and central retinal thickness (CRT), early-stage reflectance of fluorescence in FFA were also quantified. The prognostic role of early angiographic reflectance in response to treatment were evaluated. Groups were defined as high or low early fluorescence according to the reflectance level in early angiographic phase.Results: After treatment, mean BCVA was increased and mean CRT was decreased significantly (p

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