Melike BAYGIN DURAK, Banu GÜRKAN KÖSEOĞLU

Odontom Cerrahisinde Bisfosfonat Osteonekrozunu Önlemek için L-PRF Kullanımı: Vaka Raporu

İlaca bağlı çene osteonekrozu (MRONJ), antirezorptif ve/veya antianjiyojenik ilaçların kullanımına bağlı avasküler çene kemiği nekrozudur. Günümüzde antirezorptif ve antianjiyojenik ilaçlar osteoporoz, multipl miyelom, Paget hastalığı gibi hastalıklarda ve kanser metastazlarının önlenmesinde sıklıkla kullanılmaktadır. Giderek yaygınlaşan ve tedavisi zor olabilen MRONJ için birçok alternatif tedavi yöntemi önerilmiştir. Trombositten zengin kan konsantreleri bu tedavi yöntemlerinden biridir. Sunduğumuz olguda MRONJ'u önlemek için L-PRF konsantresi kullandık ve başarılı sonuçlar elde ettik.

Anahtar Kelimeler:

L-PRF, MRONJ, odontoma, gömülü diş

THE USE OF L-PRF TO PREVENT BISPHOSPHONATE OSTEONECROSIS IN ODONTOMA SURGERY: CASE REPORT

Medication related osteonecrosis of the jaw (MRONJ) is avascular jawbone necrosis due to the use of antiresorptive and/or antiangiogenic drugs. Today; antiresorptive and antiangiogenic drugs are frequently used in diseases such as osteoporosis, multiple myeloma, Paget's disease, and prevention of cancer metastases. Many alternative treatment methods have been proposed for MRONJ, which is increasingly common and can be difficult to resolve. Platelet-rich blood concentrates are one of these treatment methods. In the case we presented, we used L-PRF concentrate to prevent MRONJ and we achieved successful results.

Keywords:

L-PRF, MRONJ, odontoma, impacted tooth,

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