Murat ÖZLE, Sercan KÜÇÜKKURT, Gizem DİMİLİLER, Burcu SENGUVEN, Sedat ÇETİNER, Human Papillomavirus HPV

FOCAL EPITHELIAL HYPERPLASIA (HECK’S DISEASE) TREATED WITH USING A DIODE LASER

Fokal epitelyal hiperplazi (FEH) veya Heck hastalığı, oral mukozanın nadir görülen, asemptomatik bir proliferasyonudur. Genellikle bukkal mukoza, gingiva, dilde veya dudaklarda birden fazla sayıda, çoğu zaman asemptomatik ancak zaman zaman ağrılı ekzofitik papüller veya nodüller olarak görülür. Lezyonlar herhangi bir tedaviye bağlı olarak ya da olmadan aylar ya da yıllar içerisinde düzelebilse de, süresiz olarak devam edebilir ya da sık sık tekrarlanabilirler. Bu lezyonların, oklüzal travmaya maruz kalacağına karar verilirse veya hastada estetik endişelere neden olursa cerrahi olarak çıkarılabilirler. Kliniğimize 35 yaşında bir kadın hasta, dudağı ve bukkal mukozasında birden fazla nodül yakınması ile başvurdu. Ağız içi muayenesinde, sol bukkal mukoza ve alt dudak olmak üzere çoklu, yumuşak, pembe, inflamatuar, ekzofitik, 2-8 mm’lik papüller görüldü. Papüllerden birinin eksizyonel biyopsisinin histopatolojik incelemesi FEH tanısını teyit etti. Teşhis konulmasının ardından oral lezyonlar, diyot lazer kullanılarak seri eksizyonlarla tedavi edildi. 24 aylık takip sonrasında nüks bulgularına rastlanmamıştır. FEH büyük oranda çocukluk ve ergenlik döneminde görülen bir hastalık olmasına rağmen, bu vaka raporunda, erişkin bir kadın hastada teşhis edilen FEH, diode lazer ile tedavi edilip ve izleyen 24 aylık süreçte takibi yapılmıştır

Anahtar Kelimeler:

Fokal Epitelyal Hiperplazi, Heck Hastalığı, İnsan İapillomavirüs (HPV), Diode Lazer

FOCAL EPITHELIAL HYPERPLASIA (HECK’S DISEASE) TREATED WITH USING A DIODE LASER

Focal epithelial hyperplasia (FEH) or Heck’s disease is an uncommon asymptomatic proliferation of oral mucosa. It usually presents with multiple asymptomatic and occasionally painful exophytic papules or nodules on the buccal mucosa, gingiva, tongue or lips. Although the lesions may resolve after months or years with or without any specific treatment, they may also indefinitely persist or frequently recur. These lesions can be surgically removed if the lesions are exposed to occlusal trauma or the patient has aesthetic concerns. A 35-year-old female patient was admitted to our clinic with the complaint of multiple nodules on her lip and buccal mucosa. After an intraoral examination, we detected multiple, soft, pink, non-inflammatory, and exophytic 2 to 8 mm papules on the oral mucosa including buccal mucosa and lower lip. Histopathologic examination of the incisional biopsy of a papule confirmed the diagnosis of focal epithelial hyperplasia. Oral lesions were treated with serial partial excisions using diode laser. After 24 months of a follow-up period, there were no signs of recurrence. Although Heck’s disease is generally seen in childhood and adolescence, a rare case of FEH seen in a female adult patient who has got treatment with diode laser and 24 months of follow-up

Keywords:

Focal Epithelial Hyperplasia, Heck’s Disease, Human Papillomavirus (HPV), Diode Laser,

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