Kronik Obstrüktif Akciğer Hastalığında Noktürnal Noninvaziv Pozitif Basınçlı Ventilasyon

Kronik obstrüktif akciğer hastalığı (KOAH), zararlı gaz ve partiküllerin akciğerde yol açtığı inflamasyon nedeniyle hava yollarında ve alveollerde daralma ve solunum problemlerinin geliştiği, ilerleyici, kalıcı ve geri dönüşü olmayan bir hastalıktır. Önemli bir halk sağlığı sorunu olmaya devam etmesine rağmen tanı ve tedavi basamakları geliştirilmeye muhtaçtır.Noninvaziv pozitif basınçlı ventilasyonun KOAH alevlenmesindeki rolü ve faydaları literatürde iyi tanımlanmıştır. Stabil ilerlemiş KOAH hastalarında noktürnal NPPV kullanımı ise tartışmalı bir konu olmaya devam etmekte ve bununla ilgili literatürde henüz yeterli veri ve kanıt bulunmamaktadır. Bu derlemede stabil ilerlemiş KOAH hastalarında noktürnal NPPV kullanımının etkilerinin değerlendirilmesi amaçlandı.

Nocturnal Noninvasive Positive Pressure Ventilation in Stable Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease is characterized as a progressive and irreversible inflammatory response in the airways and alveoli because of exposure to noxious particles or gases. Excessive inflammation causes progressive, persistent, and not fully reversible structural changes and airflow limitation. Although COPD is a significant public health problem, diagnosis and treatment stages need to be improved.Nocturnal Noninvasive Positive Pressure Ventilation is one of the treatment modalities of choice for COPD exacerbation, and the role and benefits of NPPV in COPD exacerbation are well defined, but the use of nocturnalNPPV on stable severe COPDindividuals is controversial, and the evidence is not sufficient yet. This review evaluates the effects of nocturnal NPPV on stable COPD patients.

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