Özge ÇAKMAK KARAASLAN, Murat Oğuz ÖZİLHAN, Cem ÇÖTELİ, Orhan MADEN

Akut miyokard enfarktüslü hastalarda prediyabetin kardiyovasküler hastalık riskine etkisi

Amaç: Prediyabetin artmış kardiyovasküler hastalıklar (KVH) riski ve mortalite ile ilişkili olduğu bilinmektedir. Prediyabetik hastaların %70'inden fazlasında Diabetes Mellitus (DM) geliştiği bildirilmiştir. Akut miyokard enfarktüsü (AME) olan hastalarda diyabet, diyabetik olmayan hastalara kıyasla istenmeyen kardiyovasküler olay riskini 2-4 kat artırır. Bu morbidite-mortalite ilişkisi normal glukoz toleransından diyabete ilerleme aşamasında başlar. Yeni tanı almış AME ile başvuran hastalarda, hemoglobin A1c (HbA1c) değerleri kullanılarak prediyabet varlığı ile KVH riski arasındaki ilişkiyi değerlendirdik. Yöntemler: Bu çalışma retrospektif, tek merkezli olup, Mart 2019-Eylül 2020 tarihleri arasında ardışık olarak, hastanemizde AME tanısı ile koroner anjiyografi yapılan hastalar incelendi. Toplam 332 AME hastası kaydedildi; hastalar HbA1c düzeylerine göre 2 gruba ayrıldı: diyabetik olmayan grup (HbA1c

Anahtar Kelimeler:

Kardiyovasküler Hastalıklar, Miyokard enfarktüsü, Prediyabetik Durum

Impact of prediabetes on cardiovascular disease risk in patients with acute myocardial infarctions

Aim: Prediabetes is known to be associated with increased cardiovascular diseases (CVD) risk and mortality. It has been reported that more than 70% of pre-diabetic patients develop Diabetes Mellitus (DM). In patients with acute myocardial infarction (AMI), diabetes increases a 2 to 4 fold risk of adverse cardiovascular events compared to non-diabetic patients. This morbidity-mortality relationship begins in the progression phase from normal glucose tolerance to diabetes. We evaluated the relationship between the presence of pre-diabetes by using hemoglobin A1c (HbA1c) values and CVD risk in patients presenting with newly diagnosed AMI. Methods: This study was a retrospective, single-centre and we examined consecutive patients who underwent coronary angiography with a diagnosis of AMI at our hospital between March 2019 and September 2020. A total of 332 patients with AMI were enrolled; patients were divided into two groups according to their HbA1c levels: non-diabetic group (HbA1c

Keywords:

Cardiovascular Diseases, Myocardial infarction, Prediabetic State,

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