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Out-of-hospital cardiac arrests: The effectiveness of prehospital epinephrine use and ventilation management on the short-term survival of patients

Aim: The purpose of this study was to determine the effects of using a bag-valve-mask (BVM) or endotracheal intubation (EI), andadministering epinephrine during the transfer of Out-of-hospital Cardiac Arrests (OHCA) cases, and to show the effects of BVM or EI,and epinephrine use on discharge from the hospital and patient survival.Material and Methods: Totally 109 OHCA patients were included in the study. Group 1 included patients in whom return of spontaneouscirculation was achieved after Cardiopulmonary resuscitation (CPR) and who were then discharged from the hospital within 30 days.Group 2 included patients who died after emergency CPR or hospitalization. A Student’s t-test was used for normally distributedcontinuous values, and a Chi-square (χ2) test was used for numerical data.Results: Sixteen (14.7%) of the OHCA cases survived and were discharged within 30 days, and 93 (85.3%) died. The outcomes weresimilar between those who received endotracheal intubation (EI) and BVM during hospital transfer (p = 0.569). Epinephrine wasadministered to 15 (19.2%) patients in group 2 and 5 (45.4%) patients in group 1 during the transfer period, but this difference was notsignificant (p = 0.167). Logistic regression modelling did not find an association between type of airway management, epinephrineuse and 30-day discharge survival.Conclusion: The results of this study show that epinephrine had no effect on patient survival or hospital discharge in OHCA patients.Additionally, the effects of EI and BVM on 30-day survival and hospital discharge were similar.

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