Fragmented QRS; as a new sign on ECG for pre-diagnosis of non-ST elevation myocardial infarction

Fragmented QRS; as a new sign on ECG for pre-diagnosis of non-ST elevation myocardial infarction

Aim: The aim of this study is to evaluate the predictive value of fragmented QRS (fQRS) wave to detect non-ST elevation myocardial infarction (Non-STEMI).Material and Methods: The study included patients who were diagnosed with Non-STEMI in emergency department and underwent percutaneous coronary intervention in the cardiology clinic. Coronary artery circulation is anatomically divided as the left anterior descending coronary artery (LAD) (V1-V5), the left Circumflex (LCx) (I, aVL and V5,V6) and the right coronary artery (RCA) (II, III and aVF).Results: Our study included 191 patients. Significant fQRS was detected in 139 (%73) patients and ST/T was detected in 79 (%41) patients. The sensitivity, specificity, of fQRS in the inferior leads to predict RCA lesionwas 76%, 46%, respectively. The sensitivity, specificity, of ST/T in the inferior leads to “predict RCA lesion was 12%, 93%, respectively. The sensitivity, specificity of fQRS in the lateral leads to predict LCx lesion were 44% and 83%, respectively. The sensitivity, specificity of ST/T in the lateral leads to predict LCx lesion were 34%, 74%, respectively. The sensitivity, specificity of fQRS in the anterior leads to predict left LAD lesion were 34% and 82%, respectively. The sensitivity, specificity of ST/T in the anterior leads to predict LAD lesion were 38%, and 81%, respectively.Conclusion: We have compared to fQRS and ST/T on ECG; fQRS has higher sensitivity than ST/T to predict culprit coronary artery lesion. Therefore, evaluation of fQRS in addition to ST/T on ECG may be more valuable in pre-diagnosis of Non-STEMI.

___

  • Liang D, Zhang J, Lin L, et al. The Difference on Features of Fragmented QRS Complex and Influences on Mortality in Patients with Acute Coronary Syndrome.ActaCardiol Sin. 2017;33:588-95.
  • Guo R, Li Y, Xu Y, et al. Significance of fragmented QRS complexes foridentifying culprit lesions in patients withnon-ST-elevation myocardial infarction: a single-center, retrospective analysis of 183 cases. BMC Cardiovasc Disord. 2012;12:44.
  • Li Q, Wang DZ, Chen BX. Electrocardiogram in patients with acute inferior myocardial infarction due to occlusion of circumflex artery. Medicine (Baltimore). 2017;96:e6095.
  • Ahn MS, Kim JB, Yoo BS, et al. Fragmented QRS complexes are not hallmarks of myocardial injury as detected by cardiac magnetic resonance imaging in patients with acute myocardial infarction. Int J Cardiol. 2013;168:2008-13.
  • Pietrasik G, Goldenberg I, Zdzienicka J, et al. Prognostic significance of fragmented QRS complex for predicting the risk of recurrent cardiac events in patients with Q-wave myocardial infarction. Am J Cardiol. 2007;100:583-6.
  • Das MK, Michael MA, Suradi H, et al. Usefulness of fragmented QRS on a 12-lead electrocardiogram in acute coronary syndrome for predicting mortality. Am J Cardiol. 2009;104:1631-7.
  • Coons JC, Battistone S. 2007 Guideline update for unstable angina/non-ST-segment elevation myocardial infarction: focus on antiplatelet and anticoagulant therapies. Ann Pharmacother. 2008;42:989-1001.
  • Dabbagh VRK, Ayati N, Zakavi SR, et al. Comparison between fragmented QRS and Q waves in myocardial scar detection using myocardial perfusion single photon emission computed tomography. Kardiol Pol. 2015;73:437-44.
  • Das MK, Khan B, Jacob S, et al. Significance of a fragmented QRS complex versus a Q wave in patients with coronary artery disease. Circulation. 2006;113:2495-501.
  • Das MK, Saha C, Masry H, et al. Fragmented QRS on a 12-lead ECG: a predictor of mortality and cardiac events in patients with coronary artery disease. Heart Rhythm. 2007;4:1385-92.
  • Das MK, Suradi H, Maskoun W, et al. Fragmented wide QRS on a 12-lead ECG: a sign of myocardial scar and poor prognosis. Circ Arrhythm Electrophysiol. 2008;1:258-68.
  • Illescas-González E, Araiza-Garaygordobil D, Sierra Lara JD, et al. QRS-fragmentation: Case report and review of the literature. Archivos de Cardiologia de Mexico. 2017;88:124-8.
  • Korkmaz A, Yildiz A, Demir M, et al. The relationship between fragmented QRS and functional significance of coronary lesions. J Electrocardiol. 2017;50:282-6.
  • Das, MK, Zipes DP. Fragmented QRS: a predictor of mortality and sudden cardiac death. Heart Rhythm. 2009;6:S8-14.
  • Liang D, Zhang J, Lin L, et al. The difference on features of fragmented QRS complex and influences on mortality in patients with acute coronary syndrome. Acta Cardiol Sin. 2017;33:588-95.
  • Bekler A, Gazi E, Erbağ G, et al. Relationship between presence of fragmented QRS on 12-lead electrocardiogram on admission and long-term mortality in patients with non-ST elevated myocardial infarction. Turk Kardiyol Dern Ars. 2014;42:726-32.
  • El-Dosouky II, Abomandour HG. Fragmented QRS complex as a predictor of coronary artery disease in patients with acute coronary syndrome (A study from Egypt). Indian Heart J. 2017;69:289-90.
Annals of Medical Research-Cover
  • Yayın Aralığı: Aylık
  • Yayıncı: İnönü Üniversitesi Tıp Fakültesi
Sayıdaki Diğer Makaleler

Nursing education stress levels of nursing students and the associated factors

Ümmühan AKTÜRK, Hakime Aslan

Is emergent cervical radiological evaluation mandatory in isolated cranial gunshot injury?

Atilla YİLMAZ, Murteza CAKİR

Nevirapine mitigates monosodium glutamate induced neurotoxicity and oxidative stress changes in prepubertal mice

Adejoke Yetunde ONAOLAPO, Olakunle James ONAOLAPO

Does transcription factor, induced by daptomycin and vancomycin, affect HIF-1α, Chondroadherin, and COL2A1?

Numan KARAARSLAN, Mustafa DOGAN, Seyit Ali GÜMÜŞTAŞ, Yener AKYUVA, İbrahim YILMAZ, Ozkan ATES, Duygu YASAR SİRİN, Yasin Emre KAYA, Necati KAPLAN, İlknur ERDEM, Hanefi ÖZBEK

Comparison of the methods of intracorporeal knot and hem-o-lok clip to cover the stumps in laparoscopic appendectomy

Hamdi Taner TURGUT, Abdullah GÜNEŞ, Adem YUKSEL, Selim Yigit YİLDİZ, Özkan SUBAŞI, Murat COSKUN

The evaluation of physical activity levels in Turkish dialysis patients

Filiz OZDEMİR, FİLİZ KILIÇ, Fatih KURTOĞLU, Funda KARAKAŞ, Arzu DAŞKAPAN

Renal replacement Therapy in Saskat chewan: A population based analysis

Muhammad A A SİDDİQUİ, Warren BERRY

Declined vitamin D may be a trigger for hemifacial spasm

Ersin Kasim ULUSOY

Comparison of the microvessel density of gastric regions in normal and sleeve gastrectomized rats

Ayse BAHAR CEYRAN, Huseyin UZUN, Sinan YOL, Suleyman ORMAN

Germ cell testicular tumor showing spontaneous regression

Hasan GÖKÇE, Ali BEYTUR, Ali GUNES, Serhan CİMEN