Şerife SATILMIŞ, Nergis ASGIN

Evaluation of hepatitis B virus and Hepatitis C virus frequency in hemodialysis patients

Aim: This study aimed to investigate the prevalence of the hepatitis B virus and hepatitis C virus in patients undergoing hemodialysisin Karabuk city.Material and Methods: For patients presented to the Karabuk University Training and Research Hospital for hemodialysis betweenJanuary 2016 and December 2018, HBsAg, anti-HBs, and anti-HCV assays were conducted using the chemiluminescence methodand HBV DNA, HCV RNA and HCV genotyping tests were conducted using real-time polymerase chain reaction. The data wasretrospectively evaluated.Results: Of 345 patients undergoing hemodialysis, 211 (61.2%) were male and 134 (38.8%) were female. The mean ageof the patients was 62 (15–96) years. Moreover, 0.9% (n = 3) of patients were HBsAg positive and 4.3% (n = 15) wereanti-HCV positive. Three patients with HBsAg positivity were also HBV DNA positive. Of the 15 patients who were antiHCV positive, 12 were also HCV RNA positive. Of these, eight patients had the HCV genotype 1b and four patients hadthe genotype 4. Anti-HBs seropositivity was detected in 65.8% of patients. The highest Anti-HBs seropositivity rate wasobserved in patients aged

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