Retrospective evaluation of laboratory data of patients with telogen effluvium
Retrospective evaluation of laboratory data of patients with telogen effluvium
Aim: Telogen effluvium (TE) is a diffuse non-cicatricial alopecia that is frequently encountered in daily practice. This study aimed toevaluate laboratory data (whole blood count (WBC), iron (Fe), iron binding capacity (TIBC), ferritin, B12 and vitamin D, Zinc (Zn)) offemale patients with chronic TE.Material and Methods: One hundred seventy nine female patients who applied to Selçuk University Faculty of Medicine Hospital’sdermatology polyclinic between June 2015 and March 2017 with chronic TE (TE complaint of longer than 6 months) were includedin the study.Results: The mean age of the patients was 24±7.4 years. The levels of hemoglobin (HGB) (8.9%) and hematocrit (HCT) (8.9%) , meancorpuscular volume (MCV) (16.2%), Fe (16.8% ) , vitamin B12 (15.1%), Zinc (62%) and vitamin D (68.7%) were lower, TIBC (39.7%) levelwas higher than the reference range.Conclusion: Although the examinations related to the chronic TE etiology are not clear, we think that laboratory evaluation shouldbe performed for the parameters of vitamin D, B12, Zn and anemia in these patients and the remedy of their deficiencies throughsupplements may be useful in the treatment.
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- 1. Malkud S. Telogen Effluvium: A Review. J Clin Diagn Res 2015;9:1-3.
- 2. Cheung EJ, Sink JR, English Iii JC. Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. J Drugs Dermatol 2016;15:1235-37.
- 3. Yavuz IH, Yavuz GO, Bilgili SG, et al. Assessment of Heavy Metal and Trace Element Levels in Patients with Telogen Effluvium. Indian J Dermatol 2018;63:246-50.
- 4. Laskey J, Webb I, Schulman HM, et al. Evidence that transferrin supports cell proliferation by supplying iron for DNA synthesis. Exp Cell Res 1988;176:87-95.
- 5. Shrivastava SB. Diffuse hair loss in an adult female: approach to diagnosis and management. Indian J Dermatol Venereol Leprol 2009 ;75:20-8.
- 6. Karadağ AS, Ertuğrul DT, Tutal E, et al. The role of anemia and Vitamin D levels in acute and chronic telogen effluvium. Turk J Med Sci 2011;41:827-33.
- 7. Deloche C, Bastien P, Chadoutaud S, et al. Low iron stores: a risk factor for excessive hair loss in nonmenopausal women. Eur J Dermatol 2007;17:507-12.
- 8. Öztürk P, Ataseven A, Kurutaş E. Menopoz Dönemi Dışındaki Kadınlardaki Telogen Alopeside Serum Ferritin, Vit B12 ve Folat Düzeyleri. Turk J Dermatol 2012;6:117-8.
- 9. Rushton DH. Nutritional factors and hair loss. Clin Exp Dermatol. 2002;27:396-404.
- 10. Sinclair R. There is no clear association between low serum ferritin and chronic diffuse telogen hair loss. Br J Dermatol. 2002;147:982-4.
- 11. Avcı A, Avcı D, Özyurt K. Telogen Effluviumlu 563 Kadın Hastada Laboratuvar Bulguları. Bakırköy Tıp Dergisi 2015;11:120-23.
- 12. Plonka PM, Handjiski B, Popik M, et al. Zinc as an ambivalent but potent modulator of murine hair growth in vivo- preliminary observations. Exp Dermatol 2005; 14:844-53.
- 13. Finner AM. Nutrition and hair: deficiencies and supplements. Dermatol Clin 2013; 31:167-72.
- 14. Khudhair AK, Najem WS, Awni EH. Evaluation of Serum Zinc Level in Patients with Chronic Telogen Effluvium in Premenopausal Adult Females in Kirkuk City. Kerbala Journal of Pharmaceutical Sciences 2012; 4:65-72.
- 15. Özden MG, Öztaş MO, Gülekon A, et al. Kadın olgularda yaygın saç kaybı ve eşlik eden bulgular. OMÜ Tıp Dergisi 2008;25:50-6.
- 16. Cakmak I, Kalaycı M, Ekiz H, et al. Zinc deficiency as a practical problem in plant and human nutrition in Turkey: A NATO-science for stability Project. Field Crops Research 1999;60:175-88.
- 17. Gerkowicz A, Chyl-Surdacka K, Krasowska D, et al. The Role of Vitamin D in Non-Scarring Alopecia. Int J Mol Sci 2017;18:2653.
- 18. Rasheed H, Mahgoub D, Hegazy R, et al. Serum ferritin and vitamin d in female hair loss: Do they play a role? Skin Pharmacol Physiol 2013;26:101-7.
- 19. Nayak K, Garg A, Mithra P, et al. Serum Vitamin D3 Levels and Diffuse Hair Fall among the Student Population in South India: A Case-Control Study. Int J Trichology 2016; 8:160-4.
- 20. Guzel R, Kozanoglu E, Guler-Uysal F, et al. Vitamin D status and bone mineral density of veiled and unveiled Turkish women. J Womens Health Gend Based Med 2001;10:765-70.
- 21. Jackson AJ, Price VH. How to diagnose hair loss. Dermatol Clin 2013;31:21-8.
- 22. Conic RRZ, Piliang M, Bergfeld W, et al. Vitamin D Status in Scarring and Non-Scarring Alopecia. J Am Acad Dermatol 2018;18:30631-5.