Mehmet HAMAMCI

Evaluation of cognitive impairment in relapsing-remitting multiple sclerosis patients by using the montreal cognitive assessment test

Aim: Evaluating the cognitive functions of patients with relapsing-remitting multiple sclerosis (RRMS) by using the MontrealCognitive Assessment (MoCA) Test.Material and Methods: This cross-sectional study consisted of 28 RRMS patients who were diagnosed based on the revisedMcDonald 2017 criteria and 30 healthy volunteers. The MoCA test and the Expanded Disability Status Scale (EDSS) were applied.Results: The mean age of the RRMS patients was 37.21±5.61, while the mean age of the healthy volunteers was 35.6±10.09(p=0.459). 17 (60.7%) of the RRMS patients were female, 11 (39.3%) were male, while 16 (63.3%) of the control group were female,and 14 (46.7%) were male (p=0.571). The median total MoCA score was 24 (min: 15, max: 30) for the RRMS patients and 27 (min: 19,max: 30) for the healthy volunteers, and the difference was significant (p=0.006). The scores of the RRMS patients were significantlylower in terms of the MoCA sub-dimensions of executive functions, attention, language and delayed recall. There was a negative,medium-level significant correlation between the total MoCA scores and EDSS scores (r: -0.583; p

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