Epidemiological surveillance of endogenous an exogenous nosocomial infections
Epidemiological surveillance of endogenous an exogenous nosocomial infections
AbstractAim: Nosocomial infections (NIs) represent a major public health problem in developed, and even more in developing countries. Based on the origin of the pathogen, NIs are divided into endogenous caused by microorganisms of the patient’s microflora, and exogenous caused by pathogens from the patient’s environment or by the same microorganism isolated elsewhere from patient’sbody. The main aim of this research was to determine the frequency, etiology and types of NIs at the Clinic for Surgery of the University Clinical Center Tuzla.Material and Methods: 5.039 patients were prospectively followed for the development of endogenous and exogenous NIs (JanuaryDecember 2015). The definition of NI was performed using standardized the National Healthcare Safety Network (NHSN) criteria.Results: Based on continuous epidemiological surveillance, the incidence of NI was 3.51%; with a total of 177 registered infections, 24 endogenous and 153 exogenous. The most common NIs were urinary tract infections (UTIs) (14.29% endogenous and 85.71% exogenous) and surgical site infections (SSIs) (16.67% endogenous and 83.33% exogenous), p
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- 1. Garner JS, Jarvis WR, Emori TG, eet al. CDC definitions for nosocomial infections, 1988. Am J Infect Control 1988;16:128-40.
- 2. Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care–associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008;36:309-32.
- 3. Ponce-de-Leon S. The needs of developing countries and the resources required. J Hosp Infect 1991;18:376- 81.
- 4. Bobinski MA. Legal issues in hospital epidemiology and infection control. In: Mayhall CG, ed. Hospital Epidemiology and infection control. Baltimore: Williams and Wilkins 1996;1138-45.
- 5. Dixon RE. Costs of nosocomial infection and benefits of infection control programs. In: Wenzel RP, ed. Prevention and control of nosocomial infections. 1st ed. Baltimore: William and Wilkins 1987;19-26.
- 6. Larson E, Oram LF, Hedrick E. Nosocomial infection rates as an indicator of quality. Med Care 1988;26:676- 83.
- 7. Plowman R, Graves N, Griffin M, et al. The socioeconomic burden of hospital-acquired infection. London: Public Health Laboratory Service; 1999.
- 8. Wenzel RP. The economics of nosocomial infections. J Hosp Infect 1995;31:79-87.
- 9. Childress J. Hospital acquired infection, Some ethical issues. In: Wenzel RP, ed. Prevention and control of nosocomial infections. 1st ed. Baltimore: William and Wilkins 1987;49-55.
- 10. Gaynes R, Richards C, Edwards J, et al. Feeding back surveillance data to prevent hospital-acquired infections. Emerg Infect Dis 2001;7:295-8.
- 11. Tikhomirov E. WHO programme for the control of hospital infections. Chemioterapia 1987;6:148-51.
- 12. Klavs I, Luznik TB, Skerl M, et al. Prevalence of and risk factors for hospital-acquired infections in Sloveniaresults of the first national survey, 2001. J Hosp Infect 2003;54:149-57.
- 13. Gikas A, Roumbelaki M, Pediaditis J, et al. Prevalence of nosocomial infections after surgery in Greek hospitals: results of two nationwide surveys. Infect Control Hosp Epidemiol 2004;25:319-24.
- 14. Agaba P, Tumukunde J, Tindimwebwa JVB, et al. Nosocomial bacterial infections and their antimicrobial susceptibility patterns among patients in Uganda ntensive care units: a cross sectional study. BMC Res Note 2017;10:349-60.
- 15. Hague M, Sartelli, McKimm J, Abu Bakar M. Health care-associated infections – an overview. Infect Drug Resist 2018;11:2321-33.
- 16. Wenzel RP. Health care–associated infections: major issues in the early years of 21th century. Clin Infect Dis 2007;45:85-8.
- 17. Narong MN, Thongpiypoom S, Thaikul N, et al. Surgical site infections in patients undergoing major operations in a university hospital: using standardized infection ratio as benchmarking tool. Am J Infect Control 2003;31:274-9.
- 18. Pradhan NP, Bhat SM, Ghadage DP. Nosocomial infections in the medical ICU: a retrospective study highlighting their prevalence, microbiological profile and impact on ICU stay and mortality. J Assoc Physicians India 2014;62:18-21.
- 19. de Oliveira AC, Kovner CT, da Silva RS. Nosocomial infection in an intensive care unit in a Brazilian university hospital. Rev Lat Am Enfermagem 2010;18:233-9.
- 20. Doyle JS, Buising KL, Thursky KA, et al. Epidemiology of infections acquired in intensive care units. Semin Respir Crit Care Med 2011;32:115-38.
- 21. Ak O, Batırel A, Ozer S, et al. Nosocomial infections and risk factors in the intensive care unit of a teaching and research hospital: a prospective cohort study. Med Sci Monit 2011;17:29-34.
- 22. Siegel T, Mikaszewska-Sokolewicz M, MayznerZawadzka E. Epidemiology of infections at the intensive care unit. Pol Merkur Lekarski 2006;20:309- 14.
- 23. Tolera M, Abate D, Dheresa M, et al. Bacterial nosocomial infections and antimicrobial susceptibility pattern among patients admitted at Hiwot Fana Specialized University Hospital, Eastern Ethiopia. Adv Med 2018;2018