Dry eye in patients with allergic conjunctivitis

Aim: Ocular allergy is an ocular surface disease deteriorates the patient’s quality of life. This situation continues and repeatsinflammation via allergen contacts. Inflammation disrupted the tear film instability and may lead to dry eye. The aim of our study isto investigate concurrently appearing signs and symptoms of dry eye in a group of patients with symptomatic allergic conjunctivitis.Material and Methods: To be evaluated 141 patients with ocular allergy and 138 patient without ocular allergy in terms of dry eyesymptoms and signs by Oxford scheme, OSDI scores, Break up time (BUT) and Schirmer test.Results: There was a statistically significant difference was detected between the dry eye scores of the two groups.Conclusion: It may be related that ocular allergy and dry eye. Because of this relation, patients have ocular allergy evaluated in termsof dry eye simultaneously.

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1. Burcu ATB. Allerji ve Kuru Göz. MNG 2016,23:72-82.
2. Dermer H, Galor A, Hackam AS, et al. Impact of seasonal variation in meteorological conditions on dry eye severity. Clin Ophthalmol 2018;12:2471-81.
3. Kim M, Oh JH, Park CY, et al. Dry eye disease and allergic conditions: A Korean nationwide population-based study. Am J Rhinol Allergy 2016;30:397-401.
4. Huang YC, Chan WC, Wang JD, et al., Association between dry eye disease and asthma: a nationwide population-based study. PeerJ 2018;6:e5941.
5. Gulati S, Jain S. Ocular pharmacology of tear film, dry eye, and allergic conjunctivitis. Handb Exp Pharmacol 2017;242:97-118.
6. Galletti JG, Guzman M, Giordano MN, Mucosal immune tolerance at the ocular surface in health and disease. Immunology. 2017;150:397-407.
7. Bielory L, Meltzer EO, Nichols KK, et al. An algorithm for the management of allergic conjunctivitis. Allergy Asthma Proc 2013;34:408-20.
8. Dartt DA, Masli S, Conjunctival epithelial and goblet cell function in chronic inflammation and ocular allergic inflammation. Curr Opin Allergy Clin Immunol 2014;14:464- 70.
9. Dogru M, Okada N, Asano-Kato N, et al. Atopic ocular surface disease: implications on tear function and ocular surface mucins. Cornea 2005;24:18-23.
10. Villani E, Rabbiolo G, Nucci P, Ocular allergy as a risk factor for dry eye in adults and children. Curr Opin Allergy Clin Immunol 2018;18:398-403.
11. Schiffman RM, Christianson MD, Jacobsen G, et al. Reliability and validity of the ocular surface disease index. Arch Ophthalmol 2000;118: 615-21.
12. McCarty CA, Bansal AK, Livingston PM, et al. The epidemiology of dry eye in Melbourne, Australia. Ophthalmology. 1998;105:1114-9.
13. Bron AJ, Evans VE, Smith JA. Grading of corneal and conjunctival staining in the context of other dry eye tests. Cornea 2003;22:640-50.
14. Ayaki M, Kawashima M, Uchino Met al. Possible association between subtypes of dry eye disease and seasonal variation. Clin Ophthalmol 2017;11:1769-75.
15. Stull C, Valdes-Rodriguez R, Shafer BM, et al., The prevalence and characteristics of chronic ocular itch: a cross-sectional survey. Itch (Phila) 2017;2:4.
16. Chen L, Pi L, Fang J, et al. High incidence of dry eye in young children with allergic conjunctivitis in Southwest China. Acta Ophthalmol 2016;94:727-30.
17. Villani E, Strologo MD, Pichi F, et al. Dry Eye in Vernal keratoconjunctivitis: A cross-sectional comparative study. Medicine (Baltimore) 2015;94:e1648.
18. Gomes PJ, Ousler GW, Welch DL, et al. Exacerbation of signs and symptoms of allergic conjunctivitis by a controlled adverse environment challenge in subjects with a history of dry eye and ocular allergy. Clin Ophthalmol 2013;7:157-65.
19. Dogru M, Gunay M, Celik G, et al. Evaluation of the tear film instability in children with allergic diseases. Cutan Ocul Toxicol 2016;35:49-52.
20. Fujishima H, Toda I, Shimazaki J, et al. Allergic conjunctivitis and dry eye. Br J Ophthalmol 1996;80:994-7.