A rising necessity: Liver retransplantation: A single centerexperience

A rising necessity: Liver retransplantation: A single centerexperience

Aim: Compared to primary liver transplantation, poor outcomes still remain an issue for liver retransplantation.Materials and Methods: We used registry data from our liver transplantation unit to perform a retrospective cohort study on liverretransplantations performed between January 2012 and October 2019. We considered patients who underwent retransplantationat least one month after primary transplantation as the late group. Patients who had retransplantation within the first month after the first transplantation were considered the early group. We analyzed features of patients, indications, donor types, characteristics of operations, and outcomes. Results: Among 782 patients who underwent liver transplantation, 29 patients underwent retransplantation in our center. Of these 29 patients, 19 patients were in the early group, while 10 patients were in the late group. The 3-year patient survival rates were 47.3% and 80% for the early and late groups, respectively. The overall 1-year survival rate for all retransplanted patients was 58.6%. Conclusion: Despite better results reported for liver retransplantation, there are poor outcomes compared with primary transplantation,especially in the early group. However, the necessity of retransplantation increases every passing year in spite of a shortage of donors. Thus, the justification for liver retransplantation remains controversial

___

  • 1. Moon HH, Kim TS, Song S et al. Early vs. Late Liver Retransplantation: Different Characteristics and
  • Prognostic Factors. Transplant Proc 2018;50:2668-
  • 74.
  • 2. Starzl TE, Iwatsuki S, Van Thiel DH et al. Evolution of
  • liver transplantation. Hepatology 1982;2:614-36.
  • 3. Shaw BW, Gordon RD, Iwatsuki S et al. Hepatic
  • Retransplantation. Transplant Proc 1985;17:264-71.
  • 4. Crivellin C, De Martin E, Germani G et al. Risk factors
  • in liver retransplantation: a single-center experience.
  • Transplant Proc 2011;43:1110-3.
  • 5. Jiménez M, Turrión VS, Alvira LG et al. Indications
  • and results of retransplantation after a series of 406
  • consecutive liver transplantations. Transplant Proc
  • 2002;34:262-3.
  • 6. Chen GH, Fu BS, Cai CJ et al. A single-center experience
  • of retransplantation for liver transplant recipients with
  • a failing graft. Transplant Proc 2008;40:1485-7.
  • 7. Bellido CB, Martínez JM, Artacho GS et al. Have
  • we changed the liver retransplantation survival?
  • Transplant Proc 2012;44:1526-9.
  • 8. Sun CK, Chen CL, Concejero AM et al. Retransplantation
  • for end-stage liver disease: a single-center Asian
  • experience. Transplant Proc 2008;40:2503-6.
  • 9. Hwang S, Ahn CS, Kim KH et al. Liver retransplantation for adult recipients. Korean J Hepatobiliary Pancreat
  • Surg 2013;17:1-7
  • 10. Kuramitsu K, Fukumoto T, Egawa H et al. A Multicenter Japanese Survey Assessing the Long-Term Outcomes
  • of Liver Retransplantation using Living Donor Grafts.
  • Transplantation 2020;104:754-61.
  • 11. Berumen J, Hemming A. Liver Retransplantation: How
  • Much Is Too Much? Clin Liver Dis 2017;21:435-47.
  • 12. Bitterman T, Shaked A, Goldberg DS. When Living
  • Donor Liver Allografts Fail: Exploring the Outcomes
  • of Retransplantation Using Deceased Donors. Am J
  • Transplant 2017;17:1097-102.
  • 13. Marudanayagam R, Shanmugam V, Sandhu B et al.
  • Liver Retransplantation in Adults: A Single-Centre, 25-
  • year Experience. HPB (Oxford) 2010;12:217-24.
  • 14. Jeffrey AW, Delriviere L, McCaughan G et al.
  • Excellent Contemporary Graft Survival for Adult Liver
  • Retransplantation: An Australian and New Zealand
  • Registry Analysis From 1986 to 2017. Transplant
  • Direct 2019;5:472.
  • 15. Dai WC, Chan SC, Chok SHK et al. Retransplantation
  • using living-donor right-liver grafts. J Hepatobiliary
  • Pancreat Sci 2014;21:579–84.
Annals of Medical Research-Cover
  • Yayın Aralığı: Aylık
  • Yayıncı: İnönü Üniversitesi Tıp Fakültesi
Sayıdaki Diğer Makaleler

Patients with idiopathic pulmonary fibrosis referred forlung transplantation: Initial institutional experience in Turkey

Mustafa Vayvada, Ayse Nigar Halis, Pinar Atagun Guney, Sevinc Citak, Ali Yiginsu, Atakan Erkilic, Ahmet Erdal Tasci

The effects of coping strategies and relaxation exerciseson anxiety, hopelessness, life satisfaction, and well-beıng in the elderly people with diabetes: An experimental study

Hamit Coskun, Saadet Can Cicek, Seyma Ozdemir, Aynur Acikgoz, Selahattin Isko

Association between the initial blood lactate level andprognosis in patients with stroke treated with intravenous thrombolysis

Fettah Eren, Aysegul Demir, Gullu Eren

Extensively drug-resistant acinetobacter baumannii meningitis which successfully treated with tigecycline; a case report of preterm newborn

Mehmet Fatih Deveci, Ismail Kursad Gokce, Huseyin Kaya, Ramazan Ozdemir

Evaluation of hard palate asymmetry in turkish population

Ahmet Dursun, Veysel Atilla Ayyildiz

Effect of vitamin D levels on lipid, glucose, vitamin B12 andC-reactive protein in acute ischemic stroke

Cafer Caliskan, Mustafa Avci, Gulsum Caliskan, Ilhan Uysal, Nalan Kozaci

Determining the effects of Hyperoside as a protectiveagent against to testicular damage

Ayhan Tanyeli, Mustafa Can Guler, Ersen Eraslan, Fazile Nur Ekinci Akdemir

Strategies for ERCP complications: A new performer’sexperience and strategies for beginners to avoid complications

Nuri Emrah Goret, Mehmet Gokceimam

A rare cause of incarcerated inguinal hernia content: Ruptured hemorrhagic ovarian cyst

Yusuf Tanrikulu, Ceren Sen Tanrikulu, Gokhan Yilmaz

Antioxidant effects of astaxanthin on electric fieldstimulated skin and sciatic nerve tissue

Fuat Uslusoy, Dudu Dilek Yavuz, Goktug Eren Aslankoc, Arzu Yalcin, Selman Hakki Altuntas, Ilker Gunyeli