Osman KUTSAL, Murat ÇALIŞKAN, Nihat YUMUŞAK

Sweat gland carcinoma and concomitant plasmacytoma in a dog

Bu olguda pektoral bölgesinde şişlik şikayeti bulunan 5.5 yaşlı, melez, erkek bir köpekte ter bezi karsinomu ile birlikte seyreden plazmasitom olgusu tanımlandı. Pektoral bölgeden alınan biyopsi materyali makroskobik olarak, 3x5x3 cm boyutlarında, 12 gr ağırlığında, üzeri deriyle kaplı, elastik kıvamlı olup, üst yüzünde yaklaşık 2 cm çapında ülserli bir alan görüldü. Kesiti multilobuler görünümde, yer yer içlerinde seröz bir sıvının olduğu kistik yapılar bulunmaktaydı. Biyopsi materyali rutin doku takibinden sonra Hematoksilen eosin (HE) ile boyandı. Histolojik olarak, yuvarlaktan ovale kadar değişen şekillerde, hiperkromatik çekirdekli, belirgin çekirdekcikli anaplazik ter bezi epitel hücrelerinden oluşan bez yapıları görüldü. Bu bez yapılarının arasında ise çok sayıda anaplazik özellikler gösteren plazma hücrelerinin olduğu dikkati çekti.

Bir köpekte plazmasitomla seyreden ter bezi karsinomu

In this case study, sweat gland carcinoma associated with plasmacytoma was described in a 5.5-year-old male mongrel dog suffering from a swelling in the pectoral region. Macroscopically, the biopsy material taken from the pectoral region was 3x5x3 cm in size, 12 g in weight, covered with skin and of elastic consistency, and presented with an ulcerous area nearly 2 cm in diameter on the upper surface. The cross-section had a multilobular appearance and contained cystic structures, which partly contained a serous fluid. Following routine tissue processing, the biopsy material was stained with haematoxylin-eosin (HE). Histologically, glandular structures composed of anaplastic sweat gland epithelial cells, which varied from round to oval in shape and contained hyperchromatic nuclei with evident nucleoli, were observed. In-between these glandular structures many anaplastic plasma cells existed.

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