Mehmet HALIGUR, Tekinalp GELEN, Yunus ÇETİN, Özlem ÖZMEN

A case of vaginal xanthoma in a cow; First report

Bu olguda, 3 yaşlı, Holştayn ırkı bir inekte saptanan vaginal ksantom makroskobik, mikroskobik ve immunohisto- kimyasal olarak tanımlandı. Vaginadan pembe renkli, sert kıvamlı, 328 gr ağırlığındaki bir kitle cerrahi olarak uzaklaştırıldı. Histopatolojik olarak, kitle stromayla sarılı lobuler alanlardan oluşuyordu ve çok sayıda köpüklü makrofajlar, yoğun lipid materyali, az sayıda dev hücre ile kolesterol yarıkları içeriyordu. Immunohistokimyasal olarak vimentin, prolifere hücre nükleer antijen (PCNA) ve CD 68 ile pozitif; düz kas aktin (SMA), glial fibriler asidik protein (GFAP) ve S100 protein ile negatif reaksiyon saptandı. Yapılan taramalara göre bu, bir inekte saptanan ilk vaginal ksantom olgusudur.

Bir inekte vaginal ksantom olgusu; İlk rapor

A case of vaginal xanthoma in a 3-year-old Holstein cow is described on the basis of macroscopic, microscopic and immunohistochemical findings. A pink-colored mass surgically excised from the vagina was hard, nodular and 328g in weight. Histopathologically, the mass was consisted of lobular areas surrounded by a stroma and composed of numerous foamy macrophages, abundant lipid material, rarely giant cells and cholesterol clefts. Immunohistochemically, the mass was positive for vimentin, proliferating cell nuclear antigen (PCNA) and CD 68, but negative for smooth muscle actin (SMA), glial fibriler acidic protein (GFAP) and S100 protein antibodies. To the authors knowledge, this is the first report of a vaginal xanthoma in a cow.

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