Ramazan DURGUT, Suat ERDOĞAN, Ramazan GÖNENCİ

Evaluation of subclinical liver lesions in goats by fltrasonographic and biohemical analyses

Bu çalışma Hatay'ın çeşitli yerlerinden temin edilen değişik yaş ve cinsiyetten 75 Şam keçisi ve melezleri üzerinde ya-pıldı. Gerekli anamnez alındıktan sonra, bütün hayvanlar klinik, ultrasonografik ve biyokimyasal muayenelere tabi tutuldu. Klinik bulgular genellikle normal idi. Ultrasonografik olarak, hayvanların 17'sinde parenşimal, 8'inde bilier sistem ve 23'ünde de hem parenşimal hem de bilier sistem lezyonlarına birlikte rastlandı. Bu lezyonlu 48 keçide 26 parenşimal hiperekojenite, 17 kist, 10 kitle, 25 safra kesesi duvarında kalınlaşma, 3 katlanma ve 3 sediment oluşumu tek başına ya da diğer lezyonlarla birlikte gözlendi. ALT, ALP, AST, GOT, BUN, TP, CB, CHO, albumin ve glukoz konsantrasyonları lezyonlu ve lezyonsuz keçilerde normal iken, sadece LDH her ikisinde de yüksek bulundu. Bu çalışma ile karaciğer lezyonlarının klinik ve biyokimyasal anormallikler ortaya çıkmadan önce ultrasonografik olarak gözlenebileceği sonucuna varıldı.

Keçilerde subklinik karaciğer lezyonlarının ultrasonografik ve biyokimyasal olarak değerlendirilmesi

This study included 75 Damascus and its crossbreed goats from different age and sexes in the Hatay province. Following the history, all the animals were subjected to clinical, ultrasonographic and biochemical examinations. The clinical signs were generally normal. Ultrasonographically, parenchyma! lesions in 17, biliary system abnormalities in 8 and both biliary and parenchymal abnormalities in 23 animals were detected. In these 48 goats with hepatic lesions; 26 parenchymal hyperechogenicity, 17 cysts and 10 masses of parenchyma, and 25 wall thickenings, 3 foldings and 3 sediments of gallbladder were observed alone or together. LDH levels in goats with and without hepatic lesions were higher than normal reference range, whereas ALT, ALP, AST, GOT, BUN, TP, CB, CHO, albumine and glucose concentrations were in normal reference ranges. In this study, it is concluded that lesions could be observed Ultrasonographically before clinical signs and biochemical abnormalities manifest.

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1.Biller DS, Kantrowitz B, Miyabayashi T (1992): Ultrasonography of diffuse liver disease. J Vet Intern Med, 6,71-76.
2.Blanton RE, Wachira TM, Zeyhle EE, Njoroge EM, Magambo JK, Schantz PM (1998): Oxfendazole treatment for cystic hydatid disease in naturally infected animals. Antimicrob Agents Chemother, 42, 601-605.
3.Dueger EL, Moro PL, Gilman RH (1999): Oxfendazole treatment of sheep with naturally acquired hydatid disease. Antimicrob Agents Chemother, 43, 2263-2267.
4.Kaneko JJ, Harvey JW, Bruss ML (1997): Clinical Biochemistry of Domestic Animals. 5lh ed. Academic Press, Philadelphia.
5.Maxson AD, Wachira TM, Zeyhle EE, Fine A, Mwangi T W, Smith G (1996): The use of ultrasound to study the prevalence of hydatid cysts in the right lung and liver of sheep and goats in Turkana, Kenya. Int J Parasitol, 26, 1335-1338.
6.Nyland TG, Hager DA (1985): Sonography of the liver, gallbladder and spleen. Vet Clin North Am Small Anim Pract, 15, 1123-1148.
7.Nyland TG, Hager DA, Herring DS (1989): Sonography of the liver, gallbladder and spleen. Semin Vet Med Surg (Small Anim), 4, 13-31.
8.Nyland TG, Mattoon JS, Wisner ER (1995): Ultrasonography of the Liver. 52-73. In: TG Nyland, JS Mattoon (Eds), Veterinary Diagnostic Ultrasound. WB Saunders Co, Philadelphia.
9.Partington BP, Biller DS (1996): Liver. 105-130. In: RW Green (Ed), Small Animal Ultrasound. Lippincott-Raven, Philadelphia.
10.Pearson EG (1996): Diseases of the Hepatobiliary System. 913-920. In: BP Smith (Ed), Large Animal Internal Medicine. 2nd edition. Mosby, Philadelphia.
11.Sage AM, Wachira TM, Zeyhle EE, Weber EP, Njoroge E, Smith G (1998): Evaluation of diagnostic ultrasound as a mass screening technique for the detection of hydatid cysts in the liver and lung of sheep and goats. Int J Parasitol, 28, 349-353.
12.Singh AK, Behari J (1994): Ultrasound nonlinearity parameter (B/A) in biological tissues. Indian J Exp Biol, 32,281-283.
13.West HJ (1991): Evaluation of total serum bile acid concentrations for the diagnosis of hepatobiliary disease in cattle. Res Vet Sci, 51, 133-140.