Redaksiyona verildiği tarih: 22.6.1993 *Department of Toxicology, Faculty of Pharmacy, Ankara University Ankara-TURKEY rollerle kıyaslanarak anlamlı bir fark olup olmadığının araştırılması amaçlanmıştır. Ortalama serum selenyum düzeyleri akut miyokard infarktüslü hastalarda 38.59 + 15.25 /L ( n = 2 2 ) , koroner arter hastalıklı hastalarda 37.20 ± 11.44 / L (n=27) ve kontrol grubunda 63.66 + 11.71 / L (n = 21) olarak bulunmuştur. Koroner arter hastalığı olan grupla, akut miyokard infarktüslü grup arasında serum selenyum düzeylerinde önemli fark olmadığı halde (p>0.05), kontrol grubu ile her iki grup arasında anlamlı fark olduğu saptanmıştır (p>0.01)

Various epidemiological and clinical researches have been carried out in order to find out the relationship between selenium deficiency and other diseases, mainly cardiovascular diseases and certain types of cancer. In this study, we have aimed at determining serum selenium levels of the patients with acute myocardial infarction (A. M.I.), coronary artery disease (C.A.D), and the healthy control group, and investigating whether there are any significant differences between the serum selenium levels of the healthy control group and the patients with A.M.I, and C.A.D. Mean serum selenium levels were found to be 38.59 ± 15.25 / L in the patients ( n = 2 2 ) with acute myocardial infarction, 37.20 ± 1 1 . 4 4 / L in the patients (n = 27) with coronary artery disease, and 63.66 ± 11.71 / L in the healthy control group (n = 21). There was no significant difference between mean serum selenium levels of the patients with A.M.I, and C.A.D (p>0.05), but significant differences have been found between the mean serum selenium levels of the healthy control group and the other two groups mentioned above. (p<0.01)