HUZURSUZ BACAK SENDROMUNDA ISLAK KUPAYÖNTEMİNİN HASTALARIN SEMPTOM DÜZEYİ VE UYKUKALİTESİ ÜZERİNE ETKİSİ

Amaç: Huzursuz bacak sendromu (HBS), ekstremitelerde anormal duyularla giden, genellikle geceleri semptomların belirginleştiği, rahatsızlık veren, ekstremiteleri hareket ettirme isteği uyandıran kronik bir hastalıktır. HBS semptomlarının nedenleri henüz net olarak açıklanamadığı için tedavi de semptomları hafifletmeye yönelik yapılmaktadır. Bu çalışmada kupa terapinin HBS üzerine etkinliğini araştırmayı amaçladık.Materyal ve Metot: Çalışmamız Ankara Şehir Hastanesi Nöroloji ve Aile Hekimliği Polikliniklerinde Ocak 2019 ve Aralık 2019 tarihleri arasında yürütüldü. Huzursuz Bacak Sendromu tanısı almış iki hasta grubu oluşturuldu. Birinci grup mevcut haliyle pramipeksol tedavisi alan hastalardan ikinci grup ise medikal tedavi almamış hastalardan oluşturuldu. Her iki gruba bir ay ara ile 2 seans kupa terapi yapıldı. Hastalara ıslak kupa terapi öncesi ve sonrası Pittsburgh Uyku Kalite İndeksi (PUKİ) ve Huzursuz Bacak Sendromu Şiddet Skalası (HBSŞS) uygulanarak her iki grupta skorlar karşılaştırıldı.Bulgular: Birinci grupta ıslak kupa terapi uygulamasından sonra dört HBSŞS alt kategorisinde (hareket etme ihtiyacı, uyku bozukluğu, şikayetlerin günlük ortalama şiddeti ve HBSŞS toplam puanı) belirgin düşme olduğu saptandı. İkinci grupta ise, işlem sonrasında altı kategoride (HBS şikayetlerinin oranı, hareket etme ihtiyacı, uyku bozukluğu, yorgunluk ve uyku hali, HBS şikayetlerinin sıklığı, şikayetlerin günlük ortalama şiddeti) anlamlı düşme oldu. İkinci grupta PUKİ kategorilerinden uyku latansı, gündüz işlev bozukluğu ve PUKİ toplam puanı anlamlı oranda düzeldi (sırasıyla p=0,041, p=0,024, p=0,025). Prosedür sonrasında ikinci grubun HBSŞS puanlarının daha belirgin düştüğü saptandı (p=0,012).Sonuç: Medikal tedavi almayan grupta ıslak kupa terapinin semptomları azaltmada daha etkin olduğu görüldü. Özellikle hafif şikayetleri olan HBS’li hastalara semptomları azaltmak amacıyla ıslak kupa terapisi önerilebilir. Kupa terapinin etkinliğini inceleyen ileri bilimsel çalışmalarla, bu tedavinin etki mekanizmasının netleşeceği ve daha etkin ve güvenli bir şekilde uygulanabileceği düşünülmektedir

THE EFFECT OF WET CUPPING THERAPY ON PATIENTS' SYMPTOM LEVEL AND SLEEP QUALITY ON RESTLESS LEG SYNDROME

Objectives: Restless leg syndrome (RLS) is a chronic disease that goes with abnormal sensations in theextremities. Usually, the symptoms become evident at night, which causes discomfort and a desire to move.Since the causes of RLS symptoms have not been clearly explained yet, treatment is aimed at alleviating thesymptoms. In this study, we aimed to investigate the effectiveness of cupping therapy on RLS. Materials and Methods: Our study was carried out in Ankara City Hospital Neurology and Family MedicinePolyclinics between January 2019 and December 2019. The patients with the diagnosis of Restless LegSyndrome were divided into two groups. The first group consisted of patients who currently receivedpramipexole therapy, and the second group consisted of patients who received no medical treatment. Bothgroups received 2 sessions of cupping therapy at the one-month interval. Pittsburgh Sleep Quality Index (PSQI), and Restless Leg Syndrome Severity Scale (RLSSS) were applied to the patients before and after wet cuppingtherapy, and the scores were compared between groups.Results: In the first group, a significant decrease was found in four RLSS subcategories (need to move, sleepdisturbance, mean daily severity of complaints, and RLSSS total score) after wet cupping therapy. In the secondgroup, there was a significant decrease in six categories (rate of RLS complaints, need to move, sleepdisturbance, fatigue and sleepiness, frequency of RLS complaints, average daily severity of complaints) afterthe procedure. In the second group, sleep latency, daytime dysfunction and PSQI total score among the PSQIcategories improved significantly (p = 0.041, p = 0.024, p = 0.025, respectively). It was found that the RLSSscores of the second group decreased more significantly after the procedure (p = 0.012). Conclusion: It was concluded that wet cupping therapy was more effective in reducing symptoms in the groupnot receiving medical treatment. Wet cupping therapy can be recommended to reduce symptoms, especially to patients with RLS with mild complaints. With advanced scientific studies examining the effectiveness ofcupping therapy, it is thought that the mechanism of action of this treatment will be clarified and it can beapplied more effectively and safely.

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  • 1. Muramatsu K, Chikahisa S, Shimizu N, Sei H, Inoue Y. Rotigotine suppresses sleep-related muscle activity augmented by injection of dialysis patients' sera in a mouse model of restless legs syndrome. Sci Rep. 2019;9(1):16344. (doi:10.1038/s41598-019-52735-z).
  • 2. Jimenez-Jimenez FJ, Alonso-Navarro H, Garcia-Martin E, Agundez JAG. Genetics of restless legs syndrome: An update. Sleep Med Rev. 2018;39:108-21. (doi:10.1016/j.smrv.2017.08.002).
  • 3. Allen RP, Walters AS, Montplaisir J, ve ark. Restless legs syndrome prevalence and impact: REST general population study. Arch Intern Med. 2005;165(11):1286-92. (doi:10.1001/archinte.165.11.1286).
  • 4. Gupta R, Lahan V, Goel D. Restless Legs Syndrome: a common disorder, but rarely diagnosed and barely treated--an Indian experience. Sleep Med. 2012;13(7):838-41. (doi:10.1016/j.sleep.2012.03.018).
  • 5. Zobeiri M, Shokoohi A. Restless leg syndrome in diabetics compared with normal controls. Sleep Disord. 2014;2014:871751. (doi:10.1155/2014/871751).
  • 6. Silber MH. Treatment of restless legs syndrome and periodic limb movement disorder in adults [İnternet] Uptodate 2020; https://www.uptodate.com/contents/treatment-of-restless-legs-syndromeand-periodic-limb-movement-disorder-inadults?search=restless%20leg%20syndrome&source=search_result&selectedTitle=1~150&usage_type= default&display_rank=1 (Erişim tarihi: 30.11.2020).
  • 7. Hening WA, Allen RP, Earley CJ, Picchietti DL, Silber MH, Restless Legs Syndrome Task Force of the Standards of Practice Committee of the American Academy of Sleep Medicine. An update on the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. Sleep. 2004;27(3):560-83. (doi:10.1093/sleep/27.3.560).
  • 8. Hogl B, Paulus W, Clarenbach P, Trenkwalder C. Restless legs syndrome: diagnostic assessment and the advantages and risks of dopaminergic treatment. J Neurol. 2006;253 Suppl 4(4):IV22-8. (doi:10.1007/s00415-006-4005-3).
  • 9. Scholz H, Trenkwalder C, Kohnen R, Riemann D, Kriston L, Hornyak M. Dopamine agonists for the treatment of restless legs syndrome (Review). Cochrane Database Syst Rev. 2011;(3):1-150. (doi:10.1002/14651858.CD006009.pub2).
  • 10. Trenkwalder C, Winkelmann J, Inoue Y, Paulus W. Restless legs syndrome-current therapies and management of augmentation. Nat Rev Neurol. 2015;11(8):434-45. (doi:10.1038/nrneurol.2015.122).
  • 11. Anderson JC, Fritz ML, Benson JM, Tracy BL. Nerve Decompression and Restless Legs Syndrome: A Retrospective Analysis. Front Neurol. 2017;8:287. (doi:10.3389/fneur.2017.00287).
  • 12. Mardani-Kivi M, Montazar R, Azizkhani M, Hashemi-Motlagh K. Wet-cupping is effective on persistent nonspecific low back pain: a randomized clinical trial. Chinese journal of integrative medicine. 2019;25(7):502-6.
  • 13. Yoo SS, Tausk F. Cupping: East meets West. Int J Dermatol. 2004;43(9):664-5. (doi:10.1111/j.1365- 4632.2004.02224.x).
  • 14. Astin JA. Why patients use alternative medicine: results of a national study. Jama. 1998;279(19):1548- 53.
  • 15. Harris P, Finlay IG, Cook A, Thomas KJ, Hood K. Complementary and alternative medicine use by patients with cancer in Wales: a cross sectional survey. Complementary Therapies in Medicine. 2003;11(4):249- 53. (doi:10.1016/s0965-2299(03)00126-2).
  • 16. El Sayed SM, Baghdadi H, Abou-Taleb A, ve ark. Al-hijamah and oral honey for treating thalassemia, conditions of iron overload, and hyperferremia: toward improving the therapeutic outcomes. J Blood Med. 2014;5:219-37. (doi:10.2147/JBM.S65042).
  • 17. Chirali IZ. Traditional Chinese Medicine Cupping Therapy-E-Book. Elsevier Health Sciences; 2014.
  • 18. Buysse DJ, Reynolds CF, 3rd, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989;28(2):193-213. (doi:10.1016/0165-1781(89)90047-4).
  • 19. Pan W, Wang M, Li M, ve ark. Actigraph evaluation of acupuncture for treating restless legs syndrome. Evid Based Complement Alternat Med. 2015;2015:343201. (doi:10.1155/2015/343201).
  • 20. Zhang J, Yang B. Experience on treatment of restless legs syndrome with acupuncture. Journal of Acupuncture and Tuina Science. 2007;5(3):191-2.
  • 21. Xu X-M, Liu Y, Jia S-Y, Dong M-X, Cao D, Wei Y-D. Complementary and alternative therapies for restless legs syndrome: an evidence-based systematic review. Sleep medicine reviews. 2018;38:158-67.
  • 22. Kim T-H, Jung J-H, Choi Y-H, Kim B-K. Research Trend of Traditional Chinese Medicine in the Treatment of Restless Legs Syndrome. Journal of Oriental Neuropsychiatry. 2014;25(2):165-78.
  • 23. Winkelman JW, Armstrong MJ, Allen RP, ve ark. Practice guideline summary: Treatment of restless legs syndrome in adults: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Neurology. 2016;87(24):2585-93. (doi:10.1212/WNL.0000000000003388).
  • 24. Trenkwalder C, Garcia-Borreguero D, Montagna P, ve ark. Ropinirole in the treatment of restless legs syndrome: results from the TREAT RLS 1 study, a 12 week, randomised, placebo controlled study in 10 European countries. J Neurol Neurosurg Psychiatry. 2004;75(1):92-7.
  • 25. Allen RP, Earley CJ. Augmentation of the restless legs syndrome with carbidopa/levodopa. Sleep. 1996;19(3):205-13. (doi:10.1093/sleep/19.3.205).
  • 26. Ondo W, Romanyshyn J, Vuong KD, Lai D. Long-term treatment of restless legs syndrome with dopamine agonists. Arch Neurol. 2004;61(9):1393-7. (doi:10.1001/archneur.61.9.1393)
Ankara Medical Journal-Cover
  • Başlangıç: 2014
  • Yayıncı: Ankara Yıldırım Beyazıt Üniversitesi Tıp Fakültesi
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