Selin ÖZEN, Hüma BÖLÜK, Sevgi İKBALİ AFSAR

Diz Osteoartriti Semptom Şiddeti, Yaşam Kalitesi ve Uyku Kalitesi Arasındaki İlişki

Amaç: Diz osteoartriti (OA), yaşla sıklığı artan yaygın bir hastalıktır ve önemli bir morbidite nedenidir. Diz OA’lı hastalarda istirahat ve nokturnal ağrının nadiren görüldüğü yaygın bir bilgidir, ancak son çalışmalar nadir görülmediğini göstermiştir. Uyku bozukluklarının noktürnal ağrı ile ilişkili olduğu düşünülür ve artritli hastalarda uyku problemleri gelişmesi daha olasıdır. Gece ağrısı aynı zamanda depresyon ve yaşam kalitesinin düşmesi ile de ilişkilidir. Bu çalışmada, diz OA'lı hastalarda uyku kalitesini değerlendirmek ve OA şiddetiyle ağrı ve uyku bozuklukları ile kadın ve erkek hastalarda yaşam kalitesi arasındaki ilişkiyi ortaya koymak amaçlanmıştır. Materyal ve Metot: Bu kesitsel çalışma diz OA’sı olan 41 gönüllü hastayı (27 kadın, 14 erkek) kapsamakta ve 40‐65 yaş arası 6 aydan fazla diz ağrısı olan ve Kellgren‐Lawrence 'e göre 2. ve 3. derece olan hastaları kapsamaktadır. Hastalar Görsel Analog Skala (GAS), Western Ontario and McMaster Universitesi Osteoartrit İndeksi (WOMAC), Lequesne Indeksi, Pittsburg Uyku Kalitesi İndeksi (PSQI), Beck anksiyete envanteri (BAI), Beck depresyon envanteri (BDI) ve Kısa form‐36 (SF‐36) kullanılarak değerlendirildi. Bulgular: VAS, WOMAC, Lequesne indeksi, PSQI, BAI ve BDI skorları kadınlarda erkeklere göre anlamlı olarak yüksek bulundu. Erkeklerde iyi uyku kalitesi prevalansı anlamlı olarak yüksek bulundu. WOMAC skorları ile VAS, BAI ve BDI skorları arasında pozitif bir korelasyon vardı, fakat toplam PSQI skoru arasında anlamlı bir ilişki yoktu. Lequesne indeks skorları ile VAS, total PSQI, BAI ve BDI skorları arasında pozitif korelasyon vardı. WOMAC ve Lequesne indeksi ile SF‐36 arasında negatif korelasyon bulundu. Sonuç: Sonuç olarak, diz OA semptom şiddeti ile depresyon, anksiyete, uyku kalitesi ve yaşam kalitesi ilişkili bulunmuştur. Yaşam kalitesini iyileştirmek için diz OA'yı yönetmek düşünülmelidir.

Relationship Among the Symptom Severity of Knee Osteoarthritis, Quality of Life and Sleep Quality

Objectives: Knee osteoarthritis (OA) is a widespread disease that increases in the elderly and is animportant cause of morbidity. It is common knowledge that resting and nocturnal pain is rarely seen inpatients with knee OA, however latest studies showed that it is not rare. Sleep disorders are thought tobe related with nocturnal pain and it is shown that in patients with arthritis are more likely to developsleep problems. Nocturnal pain is also related with depression and decreased quality of life. This studyaims to evaluate sleep quality in patients with knee OA and to reveal the relationship between severityof knee OA, pain and sleep disorders and quality of life in female and male patients.Materials and Methods: This cross sectional study includes 41 volunteer patients (27 female,14 male)between 40‐65 years with knee OA, who suffer from knee pain for more than 6 months, and the studyincludes patients with grade 2 and 3 OA according to the Kellgren‐Lawrence classification. Patients wereevaluated using Visual Analog Scale (VAS), Western Ontario and McMaster Universities OsteoarthritisIndex (WOMAC), Lequesne Index, Pittsburg Sleep Quality Index (PSQI), Beck Anxiety Inventory (BAI),Beck Depression Inventory (BDI) and Short form‐36 (SF‐36).Results: VAS, WOMAC, Lequesne index, PSQI, BAI and BDI scores were significantly higher in femalesubjects than in male subjects. Prevalence of good sleep quality was significantly higher in male patients.There was a positive correlation between WOMAC scores and VAS, BAI and BDI scores, but there wasno significant relationship between total PSQI scores. There was a positive correlation betweenLequesne index scores and VAS, total PSQI, BAI and BDI scores. A negative correlation was foundbetween WOMAC and Lequesne index and SF‐36.Conclusion: Severity of knee OA is found associated with pain, depression and anxiety, sleep qualityand quality of life. It should be considered to manage knee OA to improve quality of life.

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