Serdar Süleyman CAN, Murat İlhan ATAGÜN, Emine Tuğçe AKÇAER, Aslı Gençay CAN

Demir Eksikliği Anemisi Üreme Çağındaki Kadınlarda Bilişsel Fonksiyonlarla İlişkili midir?

Amaç: Bu çalışmanın amacı, üreme çağındaki kadınlarda demir eksikliği anemisinin bilişsel fonksiyonlar, fiziksel fonksiyonellik, psikiyatrik morbidite, yorgunluk ve yaşam kalitesi üzerindeki etkilerini incelemekti. Materyal ve Metot: Yaşları 18‐50 arasında değişen ve demir eksikliği anemisi olan 33 kadın ve anemisi olmayan 32 sağlıklı kadın çalışmaya dahil edildi. Laboratuvar analizi, nöropsikolojik testler, Beck Depresyon Ölçeği, Beck Anksiyete Ölçeği, VAS yorgunluk, Sağlık Değerlendirme Anketi ve Kısa Form‐36 değerlendirildi. Bulgular: Gruplar arasında demografik özellikler açısından anlamlı fark saptanmadı. Demir eksikliği Anemisi olan grupta Digit Forward/Backward, Digit Span Total, Sağlık Değerlendirme Anketi, Beck Depresyon Ölçeği, Beck Anksiyete Ölçeği, Kısa Form‐36 ve yorgunluk skorları kontrol grubuna gore anlamlı olarak daha düşüktü. Korelasyon analizinde eğitim, serum demir, ferritin ve hemoglobin düzeyleri ile bilişsel test skorları ve yorgunluk arasında anlamlı ilişkili bulundu. Serum demir, ferritin ve hemoglobin düzeyleri ile Sağlık Değerlendirme Anketi, Beck Depresyon Ölçeği, Beck Anksiyete Ölçeği ve Kısa Form‐36 skorları arasında anlamlı ilişki bulundu. Sonuç: Demir eksikliği anemisi üreme çağındaki kadınlarda bilişsel fonksiyonları, fiziksel fonksiyonelliği, yaşam kalitesini, yorgunluğu, anksiyete ve depresyon semptomlarını negative yönde etkilemektedir.

Is Iron Deficiency Anemia Associated with Cognitive Functions in Reproductive‐Age Women?

Objectives: The aim of the study was to determine whether iron deficiency anemia (IDA) affectscognitive functioning, physical functioning, psychiatric morbidity, fatigue and quality of life inreproductive‐age women.Materials and Methods: Thirty‐three women aged between 18‐50 years with IDA and 32 non‐anemichealthy women were included in the study. Laboratory analyses, neuropsychological tests, BeckDepression Inventory (BDI), Beck Anxiety Inventory (BAI), VAS fatigue, Health AssessmentQuestionnaire (HAQ‐DI) and Short Form‐36 (SF‐36) were assessed.Results: There was no significant difference in demographic characteristics of the patients betweengroups. Digit Forward/Backward, Digit Span Total, HAQ‐DI, BAI, BDI, SF‐36, fatigue scores in IDAgroup were significantly lower than the controls. Correlation analysis revealed that education, serumiron, ferritin, and hemoglobin levels were associated with cognitive test scores and fatigue. Serum iron,ferritin, and hemoglobin levels were found to be associated with HAQ‐DI, BAI, BDI, and SF‐36 scores.Conclusion: IDA negatively affects cognition, physical functioning, quality of life, fatigue, symptoms ofanxiety and depression in reproductive‐age women.

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