Özlem GÜNGÖR, Kubilay ŞAHİN, Cansu ÖZTÜRK, Selma UYSAL RAMADAN, Sevinc CAN, Merve KAŞIKCI

SJÖGREN SENDROMUNDA ULTRASON ELASTOGRAFİ BULGULARI

Amaç: Sjögren Sendromunda etkilenen tüm organlarda temel histopatalojik bulgu lenfosit infiltrasyonudur Bu durum tükrük bezlerinin doku esnekliğinde değişikliğe neden olur .Bu çalışmanın amacı primer Sjögren sendromunda tükrük bezlerinde oluşan doku sertliğindeki değişikliğin shear wave elastografi ile değerlendilirmesidir. Gereç ve Yöntemler: 2016 Amerika–Avrupa uzlaşı grubu kriterleri kullanılarak iki romatolog tarafından tanısı konan,47 kadın hasta çalışmaya dahil edildi. Kontrol grubu için 41 gönüllü; benzer yaş grubu ve cinsiyette (hepsi kadın) ağız kuruluğu veya sikka semptomu olmayan , ve tükrük bezi etkilenimi yapan hastalık tanısı bulunmayan gönüllü kişilerden seçilmiştir Bütün vakaların her iki parotis ve submandibular bezleri shear wave elastografi ile değerlendirildi. Çalışma Ekim 2018- Ekim 2019 tarihleri arasında yapıldı . Bulgular: Çalışmamızda her iki parotis bezinin doku elastisite değerlerinde kPA değerlerinde kontrol grubuna kıyasla anlamlı fark mevcuttu. Fakat submandibuler bezler değerlendirildiğinde hasta ve kontrol grubu arasında anlamlı fark saptanmadı. Bizim çalışmamızda semptom süresİ ile elastisite değerleri arasında ilişki bulunmamıştır Sonuç: Primer Sjögren Sendromlu olgularda parotis bezinin shear wave elastografi tekniği ile değerlendirilmesinde shear wav elastisite değeri (kPA) değerlerinin, kontrol grubuna göre daha yüksek olması Sjögren Sendromunda SWE kullanımını kolay ,noninvasiv ve efektif bir görüntüleme yöntemi yapmaktadır.

Anahtar Kelimeler:

Sjögren sendromu, tükrük bezleri, shear wave elastografi, doku elastisititesi

ULTRASOUND ELASTOGRAPHY FINDINGS IN SJÖGREN’S SYNDROME

Background/Aims: In Sjögren’s syndrome the basic histopathology in all affected organs is progressive lymphocyte infiltration This causes a change in tissue elasticity in the major salivary glands. The purpose of this study is to investigate salivary gland stiffness in primary Sjögren’s syndrome via shear wave elastography. Material and Methods: According to the 2016 American European Consensus Group criteria, 47 female cases were included in the study as the "patient group" by two rheumatologists. A total of 41 healthy female volunteers, who were in a similar age group and had no symptoms of dry mouth or sicca, and no diagnosis of salivary gland disease, constituted the "control group" of the study .The paired parotid and submandibular glands of all subjects were examined with shear wave elastography. The study was conducted between October 2018-October 2019 Results: In our study, there was a significant difference in both parotid glands' tissue elasticity values in both speed and kPA values in cases with pSS compared to the control group. However, when the submandibular glands were evaluated, no significant difference was found between the two groups. In our study, no relationship was found between the duration of symptoms and elasticity values. Conclusions :The fact that shear wave velocity (m / sec) and elasticity value (kPA) values are higher in the evaluation of the parotid gland by SWE technique in patients with pSS than the control group makes SWE an easy, non-invasive, and effective imaging method in Sjögren's Syndrome.

Keywords:

Sjögren’s syndrome, salivary glands, shear wave elastography, tissue elasticity,

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