Recep ALANLI, Murat Bülent KÜÇÜKAY, Şahin MÜRSEL, İzzet YAVUZ, Fatma KAYMAKAMTORUNLARI DENİZ, Osman Tolga KASKATI, Metin YILDIRIMKAYA

Hemodiyaliz Hastalarında Mortaliteye Etkisi Olan Kan Parametreleri ve Ekokardiyografi Bulguları

Giriş: Bu çalışmada hemodiyalize giren hastaların demografik özellikleri, eşlik eden hastalıkları, kan parametreleri ve EKO bulguları ile mortalite arasındaki ilişkinin saptanması hedeflendi. Gereç ve Yöntem: Bu çalışma; Temmuz 2017 ile Temmuz 2021 tarihleri arasında kronik böbrek hastalığı nedeniyle düzenli hemodiyalize giren 755 hasta ile retrospektif olarak yapıldı. Onsekiz yaşından küçükler ve 60 günden az hemodiyalize girenler çalışmaya alınmadı. Bulgular: C- reaktif protein, ferritin, eritrosit dağılım hacmi, alkalen fosfataz yüksekliği, 65 yaşından büyük olmak, albumin, kalsiyum, protein eksikliği ve ejeksiyon fraksiyonu (EF) düşüklüğü ile ölüm arasında ilişki olduğu saptandı. Yaş, albümin düzeyi, hipertansiyon, hiperlipidemi ve EF düzeyleri ile mortalite arasında korelasyon bulundu. Sonuç: Hemodiyalize giren hastalarda; ileri yaş, albumin eksiliği ve EF düşüklüğü ile hiperlipidemi varlığında mortalite riski yüksek olup, bu hastaların daha dikkatli takip edilmesi gerekmektedir. Ayrıca antihipertansif ilaçların koruyucu özelliği olup, uygun olan her hastaya antihipertansif ilaç verilmesi önerilir.

Anahtar Kelimeler:

Albumin;, ejeksiyon farksiyonu, esansiyel hipertansiyon, hemodiyaliz, hiperlipidemi

Laboratory Test Paramaters and Echocardiography Findings that Affect Mortality in Hemodialysis Patients

Aim: To determine demographic characteristics, concomitant diseases, relationships between mortality and laboratory test parameters and echocardiography findings. Material and Method: Between July 2017 and July 2021, 755 patients who were undergoing hemodialysis because of chronic kidney disease regularly were inspected retrospectively. Patients under 18 years of age and patients who were undergoing hemodialysis for less than two months were excluded. Results: Age over 65 years, increased levels of C-reactive protein, ferritin, red cell diameter width, alkaline phosphatase, and decreased levels of albumin, calcium, total protein and low ejection fraction (EF) in echocardiography were found to have significant relationships. There were correlation between mortality and age, albumin levels, existence of hypertension, hyperlipidemia and low EF values. Conclusion: Advanced age, low albumin levels and low EF values and existence of hyperlipidemia and hypertension result in increased risk of mortality in hemodialysis patients. These patients must be carefully monitored. Anti-hypertensive medications have protective effects, and must be preferred whenever possible in hemodialysis patients.

Keywords:

Albumin, ventricular ejection fraction, hemodialysis, essential hypertension, hyperlipidemia,

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