Hüseyin KÖSEOĞLU, Mustafa TAHTACI, Murat BAŞARAN, Samet YAMAN, Tevfik SOLAKOĞLU, Öykü TAYFUR YÜREKLİ, Aylin DEMİREZER BOLAT, Osman ERSOY

Fundik gland polipleri ile kolon polibi ve kolorektal kanser ilişkisi

Amaç: Fundik glan polip (FGP) olan hastalarda kolorektal kanser ve kolorektal polip sıklığının artıp artmadığına dair çelişkili veriler mevcuttur. Bu çalışmanın amacı ülkemizdeki bir populasyonda FGP ile kolorektal neoplaziler arasındaki ilişkiyi ortaya koymaktır. Gereç ve yöntem: Bu çalışma retrospektif olarak yapılmış bir vaka-kontrol çalışmasıdır. Endoskopide FGP saptanan ve yakın zamanda kolonoskopi yapılmış olan hastalar FGP grubu olarak alındı. Endoskopide FGP saptanmayan ve endoskopi yapılan tarihe yakın kolonoskopi yapılmış olan hastalar kontrol grubu olarak çalışmaya dahhil edildi. Bulgular: FGP grubunda 50 vw kontrol grubunda 158 hasta çalışmaya dahil edildi. İki grup kıyaslandığında kolorektal polip sıklığının benzer olduğu izlendi, ancak FGP grubunda kolorektal kanser daha fazla saptandı. Cinsiyete göre alt grup analizi yapıldığında kadınlarda FGP grubunda kolorektal kanser riskinin artmış olduğu izlendi, ancak benzer bir ilişki erkeklerde saptanmamıştır. Sonuç: FGP olan kadın hastalarda kolorektal karsinom sıklığı FGP olmayan kadınlara göre daha fazladır.

Anahtar Kelimeler:

kolon polip, kolonoskopi, kolorektal karsinom

The relationship between fundic gland polyp and colonic polyp or colorectal carcinoma

Purpose: Conflicting results are present whether colorectal carcinoma and colorectal polyps are more frequently detectable in patients with fundic gland polyp (FGP). The aim of this study was to evaluate the interaction between FGP and colorectal neoplasms in a Turkish population. Materials and methods: A retrospectively analyzed case-control study was performed. Patients with FGP who underwent also colonoscopy were classified as the FGP group, and patients who had no FGP on endoscopy and had a colonoscopy history within six months were classified as the control group. The colorectal polyp and colorectal carcinoma prevalence were compared between groups. Results: Fifty patients were included in the FGP group and 158 patients in the control group. There was no statistically significant difference between two groups according to colorectal polyp detection, but colorectal carcinoma was more frequently seen in patients with FGP. When female patients were included in the analysis patients with FGP had a higher prevalence for colorectal carcinoma. Similar difference was not detected in men. Conclusion: Colorectal carcinoma is more common in female patients with FGP compared to female patients without FGP. purpose: Conflicting results are present whether colorectal carcinoma and colorectal polyps are more frequently detectable in patients with fundic gland polyp (FGP). The aim of this study was to evaluate the interaction between FGP and colorectal neoplasms in a Turkish population. Materials and methods: A retrospectively analyzed case-control study was performed. Patients with FGP who underwent also colonoscopy were classified as the FGP group, and patients who had no FGP on endoscopy and had a colonoscopy history within six months were classified as the control group. The colorectal polyp and colorectal carcinoma prevalence were compared between groups. Results: Fifty patients were included in the FGP group and 158 patients in the control group. There was no statistically significant difference between two groups according to colorectal polyp detection, but colorectal carcinoma was more frequently seen in patients with FGP. When female patients were included in the analysis patients with FGP had a higher prevalence for colorectal carcinoma. Similar difference was not detected in men. Conclusion: Colorectal carcinoma is more common in female patients with FGP compared to female patients without FGP.

Keywords:

colonic polyps, colonoscopy, colorectal carcinoma,

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