Dilek MEMİŞ, Turgay ALPAYDIN, Ayça ÖZDEN, Adil YURDAKOÇ, Şükriye ALAYURT, Işıl GÜNDAY

Organofosfat zehirlenmesi sonrası gelişen solunum yetmezliği ve atelektazi (Olgu sunumu)

Organofosfatlar, asetilkolinesterazı irreversibl olarak inaktive eder ve kolinerjik reseptörlerde asetilkolin birikimine neden olurlar. Santral solunum depresyonu, solunum kaslarında zayıflık, bronkospazm ve bronşial sekresyon kombinasyonuyla oluşan solunum yetmezliği yaygın ölüm nedenidir. Burada; yoğun bakım ünitesinde takip ve tedavi ettiğimiz solunum yetmezliği ve atelektazi gelişen bir organofosfat zehirlenmesi olgusunu literatürdeki çalışmaların ışığı altında tartışmayı amaçladık.

Anahtar Kelimeler:

Zehirlenme, Atelektazi, Solunum yetmezliği, Organofosfor bileşikleri

Respiratory failure and atelectasia after organophosphate poisoning (Case report)

Organophosphates act by causing irreversible inactivation of acethylcholin esterase, resulting in accumulation of acethylcholine at cholinergic receptors. Respiratory failure is the usual cause of death, often due to a combination of central respiratory depression, respiratory muscle weakness, bronchospasm and increased bronchial secretions. In this report we described and discussed a patient who developed respiratory failure and atelectesia in the intensive care unit after organophosphate poisoning.

Keywords:

Poisoning, Atelectasis, Respiratory Insufficiency, Organophosphorus Compounds,

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