Testosteron replasmanı ve kardiyovasküler yan etkileri

Testosteron (T), hipotalamus, hipofiz ve testis arasındaki bağlantı sonucu üretilen bir hormondur. T'un pek çok organ ve sistem üzerinde olumlu etkiler gösterdiği bilinmektedir. Bu faydalı etkilerine karşın, prostat ve kardiyovasküler sistem üzerinde bazı olumsuz etkiler oluşturduğu ile ilgili endişeler de vardır. T'un prostat kanseri ile olan ilişkisi son yıllarda yoğun olarak çalışılmış ve endojen T düzeyi ile T replasman tedavisinin prostat kanseri oluşumunda bir etkisinin olmadığı gösterilmiştir. Bu derlemede, mevcut uluslararası literatür gözden geçirilerek, T'un kardiyovasküler sistem üzerindeki etkileri sunulmaktadır

Testosterone replacement and its cardiovascular side effects

Testosterone (T) is a hormone produced by the connection between the hypothalamus, pituitary and testis. It is known that T has positive effects on many organs and systems. In spite of these beneficial effects, there are concerns about some adverse effects on the prostate and cardiovascular system. The association of T with prostate cancer has been intensively studied in recent years and it has been shown that endogenous T levels and T-replacement therapy have no effect on prostate cancer formation. In this review, we present the effects of T on the cardiovascular system by reviewing the current international literature

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