___

• 1. McMahon CG, Rowland DL, Abdo C, Jannini E, Chen J, Waldinger M, et al. Disorders of orgasm and ejaculation in men. In: Montorsi F, Basson R, Adaikan G, et al. (eds). Sexual Medicine: Sexual Disorders in Men and Women, Edition 2010. Paris: Health Publication Ltd; 2010.
• 2. Corona G, Jannini EA, Lotti F, Boddi V, de Vita G, Forti G, et al. Premature and delayed ejaculation: two ends of a single continuum influenced by hormonal milieu. Intern J Androl 2011;34:41–8. doi: 10.1111/j.1365-2605.2010.01059.x
• 3. McMahon CG, Althof SE, Waldinger MD, Porst H, Dean J, Sharlip ID, et al. An evidence-based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine (ISSM) ad hoc committee for the definition of premature ejaculation. J Sex Med 2008;5:1590–606. doi: 10.1111/j.1743-6109.2008.00901.x
• 4. American Psychiatric Association, Force DSMT. Diagnostic and statistical manual of mental disorders: Section I: DSM-5; 2013.
• 5. Waldinger MD, Quinn P, Dilleen M, Mundayat R, Schweitzer DH, Boolell M. A multinational population survey of intravaginal ejaculation latency time. J Sex Med 2005;2:492–7. doi: 10.1111/j.1743-6109.2005.00070.x
• 6. McMahon CG, Jannini E, Waldinger M, Rowland D. Standard operating procedures in the disorders of orgasm and ejaculation. J Sex Med 2013;10:204–29. doi: 10.1111/j.1743- 6109.2012.02824.x
• 7. Patrick DL, Althof SE, Pryor JL, Rosen R, Rowland DL, Ho KF, et al. Premature ejaculation: an observational study of men and their partners. J Sex Med 2005;2:358–67. doi: 10.1111/j.1743- 6109.2005.20353.x
• 8. Kandeel FR, Koussa VK, Swerdloff RS. Male sexual function and its disorders: physiology, pathophysiology, clinical investigation, and treatment. Endocr Rev 2001;22:342–88. doi: 10.1210/ edrv.22.3.0430
• 9. McCabe MP, Sharlip ID, Atalla E, Balon R, Fisher AD, Laumann E, et al. Definitions of Sexual Dysfunctions in Women and Men: A Consensus Statement From the Fourth International Consultation on Sexual Medicine 2015. J Sex Med 2016;13:135–43. doi: 10.1016/j.jsxm.2015.12.019
• 10. Stoleru S, Fonteille V, Cornelis C, Joyal C, Moulier V. Functional neuroimaging studies of sexual arousal and orgasm in healthy men and women: a review and meta-analysis. Neurosci Biobehav Rev 2012;36:1481–509. doi: 10.1016/j.neubiorev.2012.03.006
• 11. Georgiadis JR, Reinders AA, van der Graaf FH, Paans AM, Kortekaas R. Brain activation during human male ejaculation revisited. Neuroreport 2007;18:553–7. doi: 10.1097/ WNR.0b013e3280b10bfe
• 12. Georgiadis JR, Reinders AA, Paans AM, Renken R, Kortekaas R. Men versus women on sexual brain function: prominent differences during tactile genital stimulation, but not during orgasm. Hum Brain Mapp 2009;30:3089–101. doi: 10.1002/hbm.20733
• 13. Nathan SG. The epidemiology of the DSM-III psychosexual dysfunctions. J Sex Marital Ther 1986;12:267–81. doi: 10.1080/00926238608415413
• 14. Waldinger MD, Schweitzer DH. Retarded ejaculation in men: an overview of psychological and neurobiological insights. World J Urol 2005;23:76–81. doi: 10.1007/s00345-004-0487-8
• 15. Masters WH, Johnson VE. Human sexual inadequacy. London: Churchill; 1970. doi: 10.1017/S0021932000008117
• 16. Leiblum SR, Rosen R. Principles and practice of sex therapy, 3rd ed. New York: Guilford Press; 2000.
• 17. Perelman MA, Rowland DL. Retarded ejaculation. World J Urol 2006;24:645–52. doi: 10.1007/s00345-006-0127-6
• 18. Carani C, Isidori AM, Granata A, Carosa E, Maggi M, Lenzi A, et al. Multicenter study on the prevalence of sexual symptoms in male hypo- and hyperthyroid patients. J Clin Endocrinol Metab 2005;90:6472–9. doi: 10.1210/jc.2005-1135
• 19. Jern P, Santtila P, Witting K, Alanko K, Harlaar N, Johansson A, et al. Premature and delayed ejaculation: genetic and environmental effects in a population-based sample of Finnish twins. J Sex Med 2007;4:1739–49.
• 20. Teloken P, Nelson C, Mulhall J. 1384 Secondary delayed orgasm: patterns, correlates and predictors. J Urol 2012;187:e562.
• 21. Buvat J. Hyperprolactinemia and sexual function in men: a short review. Int J Impot Res 2003;15:373–7. doi: 10.1038/ sj.ijir.3901043
• 22. Corona G, Mannucci E, Fisher AD, Lotti F, Ricca V, Balercia G, et al. Effect of hyperprolactinemia in male patients consulting for sexual dysfunction. J Sex Med 2007;4:1485–93. doi: 10.1111/j.1743-6109.2007.00569.x
• 23. Corona G, Petrone L, Mannucci E, Ricca V, Balercia G, Giommi R, et al. The impotent couple: low desire. Int J Androl 2005;28:46– 52. doi: 10.1111/j.1365-2605.2005.00594.x
• 24. Corona G, Mannucci E, Petrone L, Giommi R, Mansani R, Fei L, et al. Psycho-biological correlates of hypoactive sexual desire in patients with erectile dysfunction. Int J Impot Res 2004;16:275– 81. doi: 10.1038/sj.ijir.3901158
• 25. Balercia G, Boscaro M, Lombardo F, Carosa E, Lenzi A, Jannini EA. Sexual symptoms in endocrine diseases: psychosomatic perspectives. Psychother Psychosom 2007;76:134–40. doi: 10.1159/000099840
• 26. Corona G, Jannini EA, Vignozzi L, Rastrelli G, Maggi M. The hormonal control of ejaculation. Nat Rev Urol 2012;9:508–19. doi: 10.1038/nrurol.2012.147
• 27. Van de Kar LD, Bethea CL. Pharmacological evidence that serotonergic stimulation of prolactin secretion is mediated via the dorsal raphe nucleus. Neuroendocrinology 1982;35:225–30.
• 28. Giuliano F. Neurophysiology of erection and ejaculation. J Sex Med 2011;8:310–5. doi: 10.1111/j.1743-6109.2011.02450.x 29. Rowland D, McMahon CG, Abdo C, Chen J, Jannini E, Waldinger MD, et al. Disorders of orgasm and ejaculation in men. J Sex Med 2010;7:1668–86. doi: 10.1111/j.1743-6109.2010.01782.x
• 30. Abdel-Hamid IA. Saleh el-S. Primary lifelong delayed ejaculation: characteristics and response to bupropion. J Sex Med 2011;8:1772– 9. doi: 10.1111/j.1743-6109.2010.02131.x
• 31. Xia JD, Han YF, Pan F, Zhou LH, Chen Y, Dai YT. Clinical characteristics and penile afferent neuronal function in patients with primary delayed ejaculation. Andrology 2013;1:787–92. doi: 10.1111/j.2047-2927.2013.00119.x
• 32. Johnson RD, Murray FT. Reduced sensitivity of penile mechanoreceptors in aging rats with sexual dysfunction. Brain Res Bull 1992;28:61–4.
• 33. Bancroft J. Human Sexuality and Its Problems, 3rd ed. Edinburgh: Churchill Livingstone, Elsevier; 2008.
• 34. Rowland DL. Penile sensitivity in men: a composite of recent findings. Urology 1998;52:1101–5.
• 35. Rowland DL, Keeney C, Slob AK. Sexual response in men with inhibited or retarded ejaculation. Int J Impot Res 2004;16:270–4. doi: 10.1038/sj.ijir.3901156
• 36. Mc Cabe M, Althof SE, Assalian P, et al. Psychological and interpersonal dimensions of sexual function and dysfunction. J Sex Med 2010;7:327–36. doi: 10.1111/j.1743-6109.2009.01618.x
• 37. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. Text Revision. Washington, DC: American Psychiatric Association; 2000.
• 38. Segraves RT. Considerations for a better definition of male orgasmic disorder in DSM V. J Sex Med 2010;7:690–5. doi: 10.1111/j.1743-6109.2009.01683.x
• 39. Wylie K, Ralph D, Levin R, Corona G, Perelman M. Comments on (considerations for a better definition of male orgasmic disorder in DSM-V). J Sex Med 2010;7:695–9. doi: 10.1111/j.1743- 6109.2009.01683_1.x
• 40. Munjack DJ, Kanno PH. Retarded ejaculation: a review. Arch Sex Behav 1979;8:139–50.
• 41. Shull GR, Sprenkle DH. Retarded ejaculation reconceptualization and implications for treatment. J Sex Marital Ther 1980;6:234–46. doi: 10.1080/00926238008406089
• 42. Perelman MA. Regarding ejaculation, delayed and otherwise. J Androl 2003;24:496.
• 43. Perelman M. Sildenafil, sex therapy, and retarded ejaculation. J Sex Educ Ther 2001;26:13–21.
• 44. Rowland DL. Psychophysiology of ejaculatory function and dysfunction. World J Urol 2005;23:82–8. doi: 10.1007/s00345- 004-0488-7
• 45. Byun JS, Lyu SW, Seok HH, Kim WJ, Shim SH, Bak CW. Sexual dysfunctions induced by stress of timed intercourse and medical treatment. BJU Intern 2013;111:E227–34. doi: 10.1111/j.1464- 410X.2012.11577.x
• 46. Kirby ED, Geraghty AC, Ubuka T, Bentley GE, Kaufer D. Stress increases putative gonadotropin inhibitory hormone and decreases luteinizing hormone in male rats. Proc Natl Acad Sci U S A 2009;106:11324–9. doi: 10.1073/pnas.0901176106
• 47. McCarthy B. Cognitive-behavioral strategies and techniques in the treatment of early ejaculation. In: Leiblum SR, Rosen RC (eds). Principles and Practice of Sex Therapy: Update for the 90s. New York: Guilford Press; 1990. p.141–67.
• 48. Corona G, Ricca V, Bandini E, Mannucci E, Lotti F, Boddi V, et al. Selective serotonin reuptake inhibitor-induced sexual dysfunction. J Sex Med 2009;6:1259–69. doi: 10.1111/j.1743- 6109.2009.01248.x
• 49. Clayton AH, Croft HA, Horrigan JP, Wightman DS, Krishen A, Richard NE, et al. Bupropion extended release compared with escitalopram: effects on sexual functioning and antidepressant efficacy in 2 randomized, double-blind, placebo-controlled studies. J Clin Psychiatry 2006;67:736–46.
• 50. Althof SE. Psychological interventions for delayed ejaculation/ orgasm. Int J Impot Res 2012;24:131–6. doi: 10.1038/ijir.2012.2
• 51. Keller Ashton A, Hamer R, Rosen RC. Serotonin reuptake inhibitor-induced sexual dysfunction and its treatment: a large-scale retrospective study of 596 psychiatric outpatients. J Sex Marital Ther 1997;23:165–75. doi: 10.1080/00926239708403922
• 52. McCormick S, Olin J, Brotman AW. Reversal of fluoxetineinduced anorgasmia by cyproheptadine in two patients. J Clin Psychiatry 1990;51:383–4.
• 53. Montorsi F, Basson R, Adaikan G, et al. (eds). Sexual Medicine: Sexual Disorders in Men and Women, Edition 2010. Paris: Health Publication Ltd; 2010.
• 54. Adeniyi AA, Brindley GS, Pryor JP, Ralph DJ. Yohimbine in the treatment of orgasmic dysfunction. Asian J Androl 2007;9:403–7. doi: 10.1111/J.1745-7262.2007.00276.x
• 55. Guay AT, Spark RF, Jacobson J, Murray FT, Geisser ME. Yohimbine treatment of organic erectile dysfunction in a dose-escalation trial. Int J Impot Res 2002;14:25–31. doi: 10.1038/sj.ijir.3900803
• 56. Ishak WW, Berman DS, Peters A. Male anorgasmia treated with oxytocin. J Sex Med 2008;5:1022–4. doi: 10.1111/j.1743- 6109.2007.00691.x
• 57. Rodriguez-Manzo G, Canseco-Alba A. Anandamide reduces the ejaculatory threshold of sexually sluggish male rats: possible relevance for human lifelong delayed ejaculation disorder. J Sex Med 2015;12:1128–35. doi: 10.1111/jsm.12866
• 58. Nickel M, Moleda D, Loew T, Rother W, Pedrosa Gil F. Cabergoline treatment in men with psychogenic erectile dysfunction: a randomized, double-blind, placebo-controlled study. Int J Impot Res 2007;19:104–7. doi: 10.1038/sj.ijir.3901483
• 59. Kruger TH, Haake P, Haverkamp J, Kramer M, Exton MS, Saller B, et al. Effects of acute prolactin manipulation on sexual drive and function in males. J Endocrinol 2003;179:357–65.
• 60. Corona G, Jannini EA, Mannucci E, Fisher AD, Lotti F, Petrone L, et al. Different testosterone levels are associated with ejaculatory dysfunction. J Sex Med 2008;5:1991–8. doi: 10.1111/j.1743- 6109.2008.00803.x
• 61. Hackett G, Cole N, Bhartia M, Kennedy D, Raju J, Wilkinson P. Testosterone replacement therapy with long-acting testosterone undecanoate improves sexual function and quality-of-life parameters vs. placebo in a population of men with type 2 diabetes. J Sex Med 2013;10:1612–27. doi: 10.1111/jsm.12146
• 62. Corona G, Isidori AM, Buvat J, Aversa A, Rastrelli G, Hackett G, et al. Testosterone supplementation and sexual function: a meta-analysis study. J Sex Med 2014;11:1577–92. doi: 10.1111/ jsm.12536
• 63. Nelson CJ, Ahmed A, Valenzuela R, Parker M, Mulhall JP. Assessment of penile vibratory stimulation as a management strategy in men with secondary retarded orgasm. Urology 2007;69:552–5. doi: 10.1016/j.urology.2006.02.048
• 64. Soeterik TF, Veenboer PW, Lock TM. Electroejaculation in psychogenic anejaculation. Fertil Steril 2014;101:1604–8. doi: 10.1016/j.fertnstert.2014.03.003
• 65. Di Sante S, Mollaioli D, Gravina GL, et al. Epidemiology of delayed ejeculation. Transl Androl Urol 2016;5:541–8. doi: 10.21037/tau.2016.05.10