Benign prostat hiperplazisi olan hastalarda PSA kullanımı
Prostat Spesifik Antijen (PSA), prostat asinilerinden salgılanan bir glikoproteindir. Prostat spesifik antijen sıklıkla prostat kanseri (PKa) için kullanılan bir test olarak düşünülmesine karşın PSA hastalık özel bir belirteç değildir, organ özel bir belirteçtir. Serum PSA düzeyinin kesinlikle prostat kanseri tanısında önemli olduğu kadar prostatın diğer benign durumlarında da önemli olduğu unutulmamalıdır. Bu derleme makalede serum PSA düzeyinin Benign Prostat Hiperplazisi (BPH) tanısında, BPH progresyonunun öngörülmesinde, BPH medikal tedavisini seçiminde ve medikal tedavi altındaki hastaların takibindeki kullanımı anlatılmaktadır.
Usage of PSA in patients with benign prostatic hyperplasia
Prostate Specific Antigen (PSA) is a glycoprotein secreted from prostate acini. Although PSA is generally considered a test used for prostate cancer (PCa), PSA is an organ-specific marker, not a disease-specific marker. It should not be forgotten that serum PSA level is important in the diagnosis of prostate cancer as well as in other benign conditions of the prostate. In this review article, the use of serum PSA in the diagnosis of BPH, in the prediction of Benign Prostatic Hyperplasia (BPH) progression, in the selection of BPH medical treatment, and in the follow-up of patients under medical treatment is described.
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