Elektrokonvulsif tedavi sırasında beyin oksijenlenmesi

Amaç: Elektrokonvülzif tedavi (EKT), etkin ve yaşam kurtarıcı bir tedavi yöntemi olmakla beraber, etkisi ve yan etkileri hala tartışılmaktadır. Çalışmamızda EKT’nin apne döneminde oksijen (O2) uygulamasının Near Infrared Spektroskopi ile serebral oksijenizayon üzerine ve EKT sonrası komplikasyonlar üzerine etkisini değerlendirmeyi amaçladık. Yöntem: Bu ileriye dönük, gözlemsel çalışmaya ilk kez EKT planlanan 40 hasta katılmıştır. Tüm hasta-lara serebral oksimetre ve bispektral indeks sensörleri (BİS) uygulandı. Hastalar nazal kanül ile 6 L/dk O2 uygula-ması yapılan hastalar Grup O (s=20), O2 uygulanmayan hastalar Grup K (s=20) olarak rastgele ikiye ayrıldı. Nöbet sırasında ve nöbetten 10 dakika sonra hemodinamik veriler, end-tidal karbondioksit (EtCO2), bölgesel serebral doku oksijen satürasyonu (rSO2 ) ve BİS değerleri ile EKT sonrası komplikasyonlar kaydedildi. Sonuçlar: Nöbet sırasında ölçülen rSO2’deki değişim ve demografik özellikler açısından gruplar arasında anlamlı bir fark saptanmadı (p>0.05). EKT sırasında desatürasyon (SpO2

Cerebral oxygenation during electroconvulsive therapy

Objective: Electroconvulsive therapy (ECT) is an effective and life-saving treatment modality, while its effects and side effects are still being discussed. In our study, we aimed to demonstrate the effect of O2 administration on the cerebral oxygenation measured by Near Infrared Spectroscopy and the complications after ECT in the apnea period of ECT. Methods: This prospective, observational study was carried out with 40 patients whom ECT had been planned and who were undergoing ECT for the first time. Cerebral oximeter sensors and Bispectral index (BIS) monitoring were applied in all patients as well as routine monitoring. The participants were randomly divided into two groups. The patients who received administration of 6 L/min O2 through nasal cannula were included in Group O (n=20), and the patients who were not administered O2 were included in Group C (n=20). Hemodynamic data after induction, during the seizures and at the 10th min after the seizures, EtCO2, regional cerebral tissue oxygen saturation (rSO2), BIS values and complications after ECT were recorded in both groups. Results: No significant difference was determined between the groups with regard to rSO2 alteration values measured during the seizures and demographic characteristics. Desaturation (SpO2

___

  • 22. Nuttall GA, Bowersox MR, Douglass SB, Mc-Donald J, Rasmussen LJ, Decker PA, et al. Morbi-dity and mortality in the use of electroconvulsive therapy. J ECT 2004; 20(Suppl.4):237-241.
  • 21. McCormick AS, Saunders DA. Oxygen saturation of patients recovering from electroconvulsive therapy. Anaesthesia 1996;51: 702-704.
  • 20. Swindells SR, Simpson KH. Oxygen saturation during electroconvulsive therapy. Br J Psychiatry 1987; 150:695-697.
  • 19. Schmidt EZ1, Reininghaus B, Enzinger C, Ebner C, Hofmann P, Kapfhammer HP. Changes in brain metabolism after ECT-positron emission tomog-raphy in the assessment of changes in glucose metabolism subsequent to electroconvulsive ther-apy--lessons, limitations and future applications. J Affect Disord 2008; 106:203-208.
  • 18. Moseley BD1, Britton JW, Nelson C, Lee RW, So E. Periictal cerebral tissue hypoxemia: a potential marker of SUDEP risk. Epilepsia 2012; 53:208-211.
  • 17. Redford D, Paidy S, Kashif F. Absolute and trend accuracy of a new regional oximeter in healthy volunteers during controlled hypoxia. Anesth Analg 2014; 119:1315-1319.
  • 16. Andropoulos DB1, Stayer SA, Diaz LK, Rama-moorthy C. Neurological monitoring for congenital heart surgery. Anesth Analg 2004; 99:1365-1375.
  • 15. Ramachandran SK, Cosnowski A, Shanks A, Turner CR. Apneic oxygenation during prolonged laryngoscopy in obese patients: a randomized, controlled trial of nasal oxygen administration. J Clin Anesth 2010; 22:164-168.
  • 14. Taha SK, Siddik-Sayyid SM, El-Khatib MF, Dagher CM, Hakki MA, Baraka A. Nasopharynge-al oxygen insufflation following pre-oxygenation using the four deep breath technique. Anaes-thesia 2006; 61:427-430.
  • 13. Lee SC. Improvement of gas exchange by apneic oxygenation with nasal prong during fiberoptic intubation in fully relaxed patients. J Korean Med Sci 1998; 13:582-586.
  • 12. Barth L. Therapeutic use of diffusion breathing in bronchoscopy. Anaesthesist 1954; 3:227-229.
  • 11. Lumb AB. Nunn’s Applied Respiratory Physiology. Seventh ed., Oxford: Churchill Livingstone; 2010.
  • 10. Kusaka T, Isobe K, Yasuda S, Koyano K, Naka-mura S, Nakamura M, et al. Evaluation of cerebral circulation and oxygen metabolism in infants using near-infrared light. Brain Dev 2014; 36:277-283.
  • 9. Fabbri F, Henry ME, Renshaw PF, Nadgir S, Ehrenberg BL, Franceschini MA, Fantini S. Bila-teral near-infrared monitoring of the cerebral con-centration and oxygen-saturation of hemoglobin during right unilateral electro-convulsive therapy. Brain Res 2003; 992(2):193-204.
  • 8. Baraka AS, Taha SK, Siddik-Sayyid SM, Kanazi GE, El-Khatib MF, Dagher CM, et al. Supple-mentation of pre-oxygenation in morbidly obese patients using nasopharyngeal oxygen insuffla-tion. Anaesthesia 2007; 62:769-773.
  • 7. Rasmussen P, Andersson JE, Koch P, Secher NH, Quistorff B. Glycopyrrolate prevents extreme bradycardia and cerebral deoxygenation during electroconvulsive therapy. J ECT 2007; 23:147-152.
  • 6. Nashef L, Walker F, Allen P, Sander JW, Shorvon SD, Fish DR. Apnoea and bradycardia during epileptic seizures: relation to sudden death in epilepsy. J Neurol Neurosurg Psychiatry 1996; 60(6):297-300.
  • 5. Surve R, Bansal S, Sriganesh K, Subbakrishna DK, Thirthalli J, Umamaheswara Rao GS. Inci-dence and risk factors for oxygen desaturation during recovery from modified electroconvulsive therapy: a prospective observational study. J Anaesthesiol Clin Pharmacol 2015; 31:99-103.
  • 4. Abrams R. Technique of electroconvulsive ther-apy: Theory. R Abrams (Ed.), Electroconvulsive Therapy, fourth ed., New York: Oxford University Press, 2002, p.142-171.
  • 3. Mankad MV, Weiner RD. Anesthesia and other medications. MV Mankad, JL Beyer, RD Weiner, AD Krystal (Eds.), Clinical Manual of Electro-convulsive Therapy, first ed., Arlington: American Psychiatric Publishing, 2010, p.81-93.
  • 2. Kadiyala PK, Kadiyala LD. Anaesthesia for electroconvulsive therapy: An overview with an update on its role in potentiating electroconvulsive therapy. Indian J Anaesth 2017; 61:373-380.
  • 1. Geretsegger C, Nickel M, Judendorfer B, Rocho-wanski E, Novak E, Aichhorn W. Propofol and methohexital as anesthetic agents for electrocon-vulsive therapy: A randomized, double-blind com-parison of electroconvulsive therapy seizure quality, therapeutic efficacy, and cognitive perfor-mance. J ECT 2007; 23:239-243.
Anadolu Psikiyatri Dergisi-Cover
  • ISSN: 1302-6631
  • Yayın Aralığı: Yılda 6 Sayı
  • Başlangıç: 2000
  • Yayıncı: -
Sayıdaki Diğer Makaleler

İstanbul ilinde öğrenim gören lise öğrencilerinde aleksitimi karakter özellikleri ile üst biliş özellikleri ve ruhsal sorunlar arasındaki ilişkinin incelenmesi

Gizem UZAL, MESUT YAVUZ, BURAK AKDENİZ, Selda ÇALLI, NURULLAH BOLAT

İlaç kullanmayan ve eş tanısı olmayan obsesif kompulsif bozukluk hastalarında plasma allopregnanolon düzeyleri

Lara Utku İNCE, Lale GÖNENİR ERBAY

Gelişim Psikolojisi Bakış Açısıyla Çocuk Suçluluğu

Asil Ali ÖZDOĞRU, Ömer AÇIKGÖZ

Investigation of autism spectrum disorder and autistic symptoms in obese children and adolescents

Çağatay UĞUR, Ahmet UÇAKTÜRK, Eda MENGEN UÇAKTÜRK

Plasma allopregnanolone levels in drug-free, comorbidity-free obsessive-compulsive disorder

Lara Utku INCE, LALE GÖNENİR ERBAY

İki uçlu bozukluk-I ve şizofreni hastalarının bakım verenlerinin yük düzeylerinin karşılaştırılması

Nurcan HANCI, ASLI SARANDÖL, Saygın EKER, CENGİZ AKKAYA

Obez çocuk ve ergenlerde otizm spektrum bozukluğu ve otistik belirtilerin araştırılması

Eda MENGEN UÇAKTÜRK, Ahmet UÇAKTÜRK, Çağatay UĞUR

Heart rate variability as an indicator of autonomous nervous system activity in children with attention deficit hyperactivity disorder

TUĞBA YÜKSEL, ÖZLEM ÖZCAN

Suicidal ideation, marital discord, and decrease effective relations among women from Iran

Mehdi KHEZELI, Seyyed-Mohammad-Mehdi HAZAVEHEI, Saeed ARIAPOORAN, Alireza AHMADI, Alireza SOLTANIAN, Forouzan REZAPUR-SHAHKOLAEI

Treatment of ADHD for at least three years may prevent long-term complications: a preliminary study on long-term prognosis of children diagnosed with ADHD at a single center in Turkey

Emel SARI GÖKTEN, Nagihan SADAY DUMAN, Burcu UÇKUN, Ali Evren TUFAN