Gebelikte Beslenmenin Kordon Kanı Yağ Asidi Düzeylerine Etkisi

Amaç: Bu çalışmada gebelikte beslenmenin kordon kanı yağ asidi düzeylerine etkisini incelemekamaçlanmıştır.Gereç ve Yöntemler: Son trimesterin başındaki toplam 33 gebenin antropometrik ve demografik verileri, ölçümler ve önceden hazırlanmış bir anket formu yoluyla toplanmıştır. Gebelerin 24saatlik besin tüketimleri kaydedilmiştir. Kordon kanlarının yağ asidi içeriği, gaz kromatografisiyöntemiyle tespit edilmiştir. Günlük beslenme ile alınan toplam yağ ve yağ asitleri, BEBİS programıyla belirlenmiş, kordon kanı yağ asidi yüzdeleriyle karşılaştırılmıştır.Bulgular: Ortalama katılımcı yaşı 32,82±3,9 yıldı. Ortalama beden kitle indeksi gebelik başındave sonunda sırasıyla 23,1±2,7 kg/m2, 28,5±3,7 kg/m2 idi. Gebelik boyunca kazanılan ortalamaağırlık 14,9±6,8 kg olarak belirlendi. Günlük enerji alımı ortalaması 1894,3±590,6 kkal olup bununkarbonhidrat, protein ve yağdan sağlanma oranları sırasıyla %40,7, %15,5 ve %43,8 idi. Günlükbeslenmedeki ve kordon kanındaki doymuş, tekli doymamış ve çoklu doymamış yağ asitlerininoranları sırasıyla %39,7–47,5, %38,6–20,8 ve %21,7–32 olarak saptandı. Kadınların doymuş yağasitlerini önerilerin üstünde, tekli ve çoklu doymamış yağ asitlerini ise önerilen miktarda aldıklarıgözlendi.Tartışma ve Sonuç: Beslenmeyle alınan protein miktarının, kordon kanı doymuş yağ asitleriyleilişkili olduğu görülmüştür. Doymuş yağ ve protein içeriği yüksek beslenme alışkanlıklarının, kordon kanı doymuş yağ asidi düzeylerini artırdığı gözlemlenmiştir. Gebelikte anne sağlığı ve normal fetal gelişim için yeterli ve dengeli beslenmenin şart olduğu ve bu konuda ileri çalışmalaraihtiyaç olduğu sonucuna varılmıştır.

Effects of Nutrition during Pregnancy on Levels of Cord Blood Fatty Acids

Aim: This study aimed to assess the effects of nutrition during pregnancy on levels of cord blood fatty acids. Materials and Methods: Demographic and anthropometric data of a total of 33 pregnant women at the beginning of the last trimester were obtained by measurement and use of a questionnaire prepared previously. 24-hour food consumption was also recorded. Fatty acid content of cord blood was determined by gas chromatography. Fatty acids intake during daily nutrition was analyzed by the BEBIS software and compared with cord blood fatty acids percentages. Results: The mean participant age was 32.82±3.9 years. The mean body mass index at the beginning and end of pregnancy was 23.1±2.7 kg/m2 and 28.5±3.7 kg/m2, respectively. The mean weight gain during pregnancy was 14.9±6.8 kg. The mean daily energy intake was 1894.3±590.4 kcal, of which 40.7% was derived from carbohydrates, 15.5% proteins and 43.8% fats. The rates of saturated, monounsaturated, and polyunsaturated fatty acid intake during daily nutrition and in cord blood were 39.7–47.5%, 38.6–20.8%, and 21.7–32%, respectively. We found that the women’s saturated fatty acid intake exceeded the recommended levels while their intake of monounsaturated and polyunsaturated fatty acids conformed with the recommendations. Discussion and Conclusion: We observed that the amount of protein intake during nutrition was associated with cord blood fatty acids. We found that nutritional habits with an increased intake of saturated fatty acids and proteins increased the levels of cord blood fatty acids. We conclude that adequate and balanced nutrition during pregnancy is crucial for both maternal health and normal fetal development, and that there is a need for further relevant studies.

___

  • 1. Morrison JL, Regnault TRH. Nutrition in pregnancy: optimising maternal diet and fetal adaptations to altered nutrient supply. Nutrients. 2016;8(6):342.
  • 2. T.C. Sağlık Bakanlığı. 2016. Türkiye Beslenme Rehberi 2015. Erişim: https://dosyasb.saglik.gov.tr/ Eklenti/10915,tuber-turkiye-beslenme-rehberipdf.pdf (erişildi: 31.1.2018).
  • 3. Garipağaoğlu M, Budak N, Elmacıoğlu F, Bulut A. The evaluation of nutritional status of a group of pregnant women living in Istanbul. Türk Aile Hek Derg. 2007;11(3):27–31.
  • 4. Food and Agriculture Organization of the United Nations. 2010. Fats and Fatty Acids in Human Nutrition. Erişim: www.fao.org/3/a-i1953e.pdf (erişildi: 31.1.2018).
  • 5. Krauss-Etschmann S, Shadid R, Campoy C, Hoster E, Demmelmair H, Jiménez M ve ark. Effects of fish-oil and folate supplementation of pregnant women on maternal and fetal plasma concentrations of docosahexaenoicacid and eicosapentaenoic acid: a European randomized multicenter trial. Am J Clin Nutr. 2007;85(5):1392–400.
  • 6. Huffman SL, Harika RK, Eilander A, Osendarp SJ. Essential fats: how do they affect growth and development of infants and young children in developing countries? A literature review. Matern Child Nutr. 2011;7(3):44– 65.
  • 7. Lauritzen L, Brambilla P, Mazzocchi A, Harsløf LB, Ciappolino V, Agostoni C. DHA effects in brain development and function. Nutrients. 2016;8(1):1–7.
  • 8. Franke C, Verwied-Jorky S, Campoy C, Trak-Fellermeier M, Decsi T, Dolz V ve ark. Dietary intake of natural sources of docosahexaenoic acid and folate in pregnant women of three European cohorts. Ann Nutr Metab. 2008;53(3–4):167–74.
  • 9. Linseisen J, Bergstrom E, Gafa L, CA González, A Thiébaut, A Trichopoulou ve ark. Consumption of added fats and oils in the European Prospective Investigation into Cancer and Nutrition (EPIC) centres across 10 European countries as assessed by 24-hour dietary recalls. Public Health Nutr. 2002;5(6B):1227–42.
  • 10. Duttaroy AK. Transport of fatty acids across the human placenta: a review. P Lip Res. 2009;48(1):52–61.
  • 11. Leikin-Frenkel AI. Is there a role for alpha-linolenic acid in the fetal programming of health. J Clin Med. 2016;23:5(4):40.
  • 12. Koletzko B, Lien E, Agostoni C, Böhles H, Campoy C, Cetin I ve ark. The roles of long-chain polyunsaturated fatty acids in pregnancy, lactation and infancy: review of current knowledge and consensus recommendations. J Perinat Med. 2008;36(1):5–14.
  • 13. “Bebispro for Windows, Stuttgart, Germany; Turkish Version (Bebis 4), Istanbul, 2004. Program Uses Data From Bundeslebensmittelschlüssel (BLS) 11.3 and USDA 15.”
  • 14. Institute of Medicine of National Academies. 2005. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Erişim: www.nal.usda.gov/fnic/DRI/DRI_Energy/ energy_full_report.pdf (erişildi: 29.1.2018).
  • 15. World Health Organisation. 2014. Global Status Report on Noncommunicable Diseases. Erişim: www.who.int/ gho/ncd/risk_factors/bmi_text/en (erişildi: 29.1.2018). 16. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol. 1959;37(8):911–7.
  • 17. Wennberg AL, Lundqvist A, Hogberg U, Sandström H, Hamberg K. Women’s experiences of dietary advice and dietary changes during pregnancy. Midwifery. 2013;29(9):1027–34.
  • 18. Dubois L, Diasparra M, Bedard B, Colapinto CK, Fontaine-Bisson B, Morisset AS ve ark. Adequacy of nutritional intake from food and supplements in a cohort of pregnant women in Québec, Canada: the 3D Cohort Study. Am J Clin Nutr. 2017;106(2):541–8.
  • 19. Fujita M, Tsubota M, Ishida M. A qualitative study of women’s perceptions of provider advice about diet and physical activity during pregnancy. Int J Nurs Clin Pract. 2015;115(2):1–4.
  • 20. Sarıyıldız L, Akdağ T. Some Haematological and metabolic changes observed in pregnancy. J Clin Anal Med. 2013;4(3):245–8.
  • 21. McGowan CA, McAuliffe FM. Maternal dietary patterns and associated nutrient intakes during each trimester of pregnancy. Public Health Nutr. 2012;16(1):97–107.
  • 22. Blumfield LM, Collins EC. High-protein diets during pregnancy: healthful or harmful for offspring? Am J Clin Nutr. 2014;100(4):993–5.
  • 23. Mihan JA, Rodriguez J, Christie C, Sadeghi M, Zerbe T. The role of maternal dietary proteins in development of metabolic syndrome in offspring. Nutrients. 2015;7(11):9185–217.
  • 24. Ferrari RM, Siegariz AM, Evenson KR, Moos MK, Carrier KS. A qualitative study of women’s perceptions of provider advice about diet and physical activity during pregnancy. Patient Educ Couns. 2013;91(3):372–7.
  • 25. Bascunan KA, Valenzuela R, Chamorro R, Valencia A, Barrera C, Puigrredon C ve ark. Polyunsaturated fatty acid composition of maternal diet and erythrocyte phospholipid status in Chilean pregnant women. Nutrients. 2014;6(11):4918–34.
  • 26. World Health Organisation. 2012. Sodium Intake for Adults and Children. Erişim: www.who.int/nutrition/ publications/guidelines/sodium_intake_printversion. pdf (erişildi: 31.3.2018).