Statin kullanımına bağlı pankreatik enzim yükselmesi-vaka sunumu

Statin kullanımıyla birlikte kas ağrıları, karaciğer enzim yüksekliği ve rabdomyoliz görülebilmektedir. Pankreas hasarı ve buna bağlı lipaz yüksekliği statinin nadir görülen ciddi istenmeyen etkilerindendir. Bu vaka sunumunda, statin kullanımından sonra lipaz seviyelerinde yükselme görülen, serebrovasküler hastalık ve prostat kanseri öyküsü bulunan 61 yaşında bir erkek hastayı değerlendirdik. Bu hastada olası pankreatik hasar görülen hastada farklı statin gruplarını denedik ve statin kullanımına bağlı olası pankreas hasar mekanizmalarını ele aldık.

Anahtar Kelimeler:

pankreas, lipaz, statin

A case of pancreatic enzyme elevation due to use of statins

It is well known that statin usage is linked with side effects such as miyalgias, hepatic enzyme elevation and rabdomyolisis. Pancreatic injury and lipase elevation may be a rare side effect of statins. In this case report, we present a 61-year-old male with the history of cerebrovascular disease (CVD) and prostate cancer which experienced elevation of lipase levels after use of statins. We tried different types of statins for the patients condition of pancreatic injury and in this case report, the possible reasons of statin induced pancreatic injury are underlined.

Keywords:

pancreas, statin, lipase,

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