Tuğçe TOPOĞLU ÇAĞLAR, Azar ABİYEV, Özlem ERDEM, Murat KEKİLLİ, İbrahim DOĞAN

Otoimmün hepatit tanılı hastada azatioprin tedavisi sonrası gelişen Kaposi sarkomu

Kaposi sarkomu, insan herpes virüsü-8 ile ilişkili mezenkimal bir neoplazmdır. Genellikle birincil veya ikincil immün yetmezliği olan hastalarda bulunur. Azatioprin gibi immünomodülatör ilaçlar otoimmün hepatit hastalığında etkilidir, ancak bunların kullanımı toksisite endişeleri nedeniyle sınırlıdır. Burada, otoimmün hepatit hastalığı için azatioprin tedavisi alan ve sonrasında Kaposi sarkomu gelişen, insan immün yetmezlik virüsü negatif bir olguyu sunuyoruz.

Anahtar Kelimeler:

Otoimmün hepatit, azatioprin, Kaposi sarkomu

Kaposi sarcoma development after azathioprine use in a patient with autoimmune hepatitis: A case report

Kaposi sarcoma is a mesenchymal neoplasm associated with human herpes virus-8. It is usually found in patients who have primary or secondary immune deficiency. Immunomodulatory drugs such as azathioprine are effective in the treatment of autoimmune hepatitis. However, their use is limited due to toxicity concerns. We present an human immmunodeficiency virus-negative case who received azathioprine treatment for autoimmune hepatitis and subsequently developed Kaposi sarcoma.

Keywords:

Autoimmun hepatitis, azathioprine, Kaposi sarcoma,

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