Soraa SOHEILY, Haleh GHAVAMI, Moloud RADFAR, Hamid Reza KHALKHALI, Shams Aldin SHAMSI

Tip 2 diyabetli hastalarda yaşam tarzı müdahalelerinin diyabetik periferik nöropati şiddeti üzerine etkisi, randomize klinik çalışmanın sonucu

Amaç: Diyabetik periferik nöropati (DPN) diyabetin en sık karşılaştığı ve sıkıntılı bir komplikasyondur ve büyük bir morbiditeye yol açar ve diyabet bakımı için büyük bir ekonomik yük oluşturur. Nöropati diyabetli kişilerin yarısından fazlasında gelişir. Ayrıca, ağrı, duyusal kayıp, yürüme instabilitesi, düşme ile ilişkili yaralanma, ayak ülseri ve amputasyon nedeniyle, DPN yaşam kalitesinin azalmasının temel nedenidir. Bu çalışmanın amacı, ayakta tedavi edilen diyabet tip 2 hastalarda; yaşam tarzı müdahalelerinin diyabetik nöropati şiddeti üzerine etkilerini değerlendirmekti. Gereç ve Yöntem: Bu klinik çalışma, DPN’si olan ve rastgele yöntemi ile; müdahale ya da kontrol grubuna ayrılanan, 74 hasta üzerinde gerçekleştirildi.Kan şekerini düşürmek, fiziksel aktiviteyi arttırmak, kilo kaybını teşvik etmek, ihtiyatlı beslenme ve ayak bakımı için stratejileri vurgulayan yaşam tarzı üzerine dört eğitim oturumu ile başlanan yaşam tarzı müdahaleleri müdahale grubunda uygulanmaya başladı. Her eğitim seansi 1.5 saat sürdü. Daha sonra hastalar 12 hafta boyunca takip edildiler ve bu dönemde yaşam tarzı müdahaleleri konusunda danışmanlık aldılar. Her iki grupta da DPN`nin şiddeti, çalışmanın başlangıcında, ve 12 haftalık danışmanlık sonunda modifiye Toronto Clinical Neuropathy Score (mTCNS) kullanılarak ölçüldü. Bulgular: Çalışma gruplarının DNP şiddeti, yaşam tarzı müdahaleleri öncesi ve sonrası, ortalamaları arasındaki farklılıkların karşılaştırıldığında anlamlı bir fark bulundu (p

Effect of lifestyle interventions on diabetic peripheral neuropathy in patients with type 2 diabetes, result of a randomized clinical trial

Objectives: Diabetic peripheral neuropathy (DPN) is the most common and troublesome complication of diabetes leadingto great morbidity and resulting in a huge economic burden for diabetes care. Over half of people with diabetes developneuropathy. Also, DPN is a major cause of reduced quality of life due to pain, sensory loss, gait instability, fall-related injury,and foot ulceration and amputation. The aim of this study was evaluating the effects of lifestyle interventions on diabeticneuropathy severity in diabetes type 2 outpatients.Methods: This clinical trial conducted on 74 patients with DPN that divided with random allocation into intervention or control group. The lifestyle interventions applied in the intervention group beginning four educational sessions on lifestyle thatemphasize strategies for lowering blood sugar, increasing physical activity, promoting weight loss, prudent diet, and foot caring. Each session was lasted for1.5 hour. Then patients followed for 12 weeks. During this period, they received counseling onmentioned lifestyle interventions. DPN severity in both groups measured using modified Toronto Clinical Neuropathy Score(mTCNS) at the beginning of study and at the end of counseling for 12 weeks.Results: Comparing differences of mean of DNP severity before and after lifestyle intervention between two groups of study,there was a significant difference (p

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