İSKENDER KARA, Lütfi YAVUZ, Berit Gökçe CEYLAN, Füsun EROĞLU

Preoperatif üç farklı yolla uygulanan lornoksikamın postoperatif analjezi üzerine etkisi

Bu çalışmada preoperatif lornoksikamın PO, İM ve İV uygulamasının postoperatif ağrıyı önlemedeki etkisini araştırdık. ASA I-II grubuna giren, 18-65 yaş arası 40 olgu randomize dört gruba ayrıldı. 8 mg lornoksikam operasyondan 1 saat önce oral, İM, veya İV (Grup PO, Grup İM, Grup İV) verildi. Kontrol grubuna (Grup K) analjezi yapılmadı. Postoperatif ilk analjezik gereksinimi zamanı, tüketilen ilaç miktarları, VAS ve VRS ağrı skorları kaydedildi. VAS ≥ 3 olduğu zaman lornoksikam infüzyonu HKA cihazı ile verildi. Grup K’da, diğer gruplara göre postoperatif ağrı başlama süresinin daha kısa; postoperatif 2. saatte VAS ve VRS skorları daha yüksek ve total lornoksikam tüketiminin ise daha fazla olduğu saptandı. Grup PO, İM ve İV arasında ağrı başlama süresi ve total lornoksikam tüketimi açısından anlamlı fark bulunmadı. Preoperatif 8 mg lornoksikam kullanmı postoperatif ağrı başlama süresini uzatmakta ve analjezik ihtiyacını azaltmaktadır. PO, IM, İV uygulamalar arasında analjezik etki açısından fark saptanmamıştır.

Anahtar Kelimeler:

Ameliyat sonrası dönem, Ağrı yönetimi, Ağrı, ameliyat sonrası, Analjezi

The effect of three different lornoxicam administration on postoperative analgesia

In this study we evaluated the postoperative analgesic efficacy of lornoxicam PO, IM and IV administration preoperatively. Fourty patients, aged between 18-65 years, ASA I-II class, were randomized to four groups. Lornoxicam 8 mg was administired PO, IM, IV (Group PO, Group IM, Group IV) 1 hour before the operation. Analgesia was not performed in control group (Group C). First analgesic requirement time, analgesic consumption and the VAS and VRS pain scores were recorded postoperatively. When VAS 3 patient controlled analgesia with lornoxicam was begun. We found that first analgesic requirement time was shorter, postoperative 2nd hour VAS and VRS scores and drug consumptions were higher in Grup C cases according to the other groups. There was no significant difference in first analgesic requirement time and analgesic consumption. Preoperative administration of 8 mg lornoxicam delayed the first analgesic requirement time and decreased total analgesic requirement. There was no difference on analgesic effect between PO, IM, and IV administrations.

Keywords:

Postoperative Period, Pain Management, Pain, Postoperative, Analgesia,

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