Resul YILMAZ, Damlanur ÜSTÜN, SEMA TUNCER UZUN, Ruhiye REİSLİ, Şeyda TÜRK

A probable case of movement disorder (Tardyskinesia) due to duloive dxetine treatment

Tardive dyskinesia and tardive dystonia are caused by dopamine receptor blocking agents, mostly antipsychotics and sometimes antidepressants or calcium channel blockers. Duloxetine is a serotonin-noradrenaline reuptake inhibitor used in the treatment of diabetic neuropathic pain and fibromyalgia, as well as major depression. In this case, we aimed to discuss the tardive dyskinesia-like appearance of a patient using duloxetine due to fibromyalgia.

Duloksetin tedavisine bağlı beklenmedik bir hareket bozukluğu olgusu (Tardif diskinezi)

Tardif diskineziye ve tardif distoniye, çoğunlukla dopamin reseptör bloke edici ajanlar, bazen de antidepresanlar veya kalsiyum kanal blokerleri neden olur. Duloksetin, diyabetik nöropatik ağrı ve fibromiyaljinin yanı sıra majör depresyon tedavisinde kullanılan bir serotonin-noradrenalin geri alım inhibitörüdür. Bu olguda fibromiyaljiye bağlı duloksetin kullanan bir hastanın tardif diskinezi benzeri görünümünü tartışmayı amaçladık.

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Trivedi MH, Desaiah D, Ossanna MJ, Pritchett YL, Brannan SK, Detke MJ. Clinical evidence for serotonin and norepinephrine reuptake inhibition of duloxetine. Int Clin Psychopharmacol 2008;23(3):161–9.

Jankovic J. Tardive syndromes and other drug-induced movement disorders. Clin Neuropharmacol 1995;18(3):197–214.

Çavuşoğlu H. Bazal ganglionlar-Motor fonksiyonları. In: Guyton AC, Hall JE, editors. Tıbbi Fizyoloji. 9th ed. İstanbul: Alemdar; 1996. p. 728.

Remington GJ. The Pisa syndrome: possible role for serotonin and noradrenaline. J Clin Psychopharmacol 1988;8(3):228–9.

Trugman JM, Leadbetter R, Zalis ME, Burgdorf RO, Wooten GF. Treatment of severe axial tardive dystonia with clozapine: case report and hypothesis. Mov Disord 1994;9(4):441–6.

Leo RJ. Movement disorders associated with the serotonin selective reuptake inhibitors. J Clin Psychiatry 1996;57(10):449–54.

Yassa R, Camille Y, Belzile L. Tardive dyskinesia in the course of antidepressant therapy: a prevalence study and review of the literature. J Clin Psychopharmacol 1987;7(4):243–6.

Clayton AH. Antidepressant-induced tardive dyskinesia: review and case report. Psychopharmacol Bull 1995;31(2):259–64.

Dubovsky SL, Thomas M. Tardive dyskinesia associated with fluoxetine. Psychiatr Serv 1996;47(9):991–3.

Boffa E, Lofchy J. Paroxetine and tardive akathisia. Can J Psychiatry 2000;45(2):196.

Botsaris SD, Sypek JM. Paroxetine and tardive dyskinesia. J Clin Psychopharmacol 1996;16(3):258–9.

Lee Y, Yeh WC, Chong MY, Lin PY, Chang YY. Venlafaxine and tardive blepharospasm: a case report. Prog Neuropsychopharmacol Biol Psychiatry 2007;31(5):1139–40.

L Lin CC, Lin PY, Lee Y, Chang YY, Chen CH. Tardive dystonia and tardive sensory syndrome related to trazodone: a case report. Prog Neuropsychopharmacol Biol Psychiatry 2008;32(6):1609–10.

Deuschle M, Mase E, Zink M. Dyskinesia during treatment with duloxetine. Pharmacopsychiatry 2006;39(6):237–8.

Chen PY, Lin PY, Tien SC, Chang YY, Lee Y. Duloxetine-related tardive dystonia and tardive dyskinesia: a case report. Gen Hosp Psychiatry 2010;32(6):646.e9–11

Kenney C, Hunter C, Davidson A, Joseph J. Metoclopramide, an increasingly recognized cause of tardive dyskinesia. J Clin Pharmacol 2008;48(3):379–84.